Findings

What do systematic reviews say?

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

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No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Acupuncture vs no treatment

Adverse events at end of treatment · women with PMS

1 finding from 1 review

Acupuncture and acupressure for premenstrual syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Acupuncture vs no treatment

Specific PMS symptoms ‐ not measured · women with PMS

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture and acupressure for premenstrual syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

In vitro maturation vs in vitro fertilisation

Live birth · subfertile women with polycystic ovarian syndrome undergoing assisted reproduction

The review found no eligible studies for this question.

1 finding from 1 review

In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

In vitro maturation vs in vitro fertilisation

Miscarriage · subfertile women with polycystic ovarian syndrome undergoing assisted reproduction

The review found no eligible studies for this question.

1 finding from 1 review

In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

In vitro maturation vs in vitro fertilisation

Clinical pregnancy · subfertile women with polycystic ovarian syndrome undergoing assisted reproduction

It is very uncertain whether in vitro maturation changes clinical pregnancy compared with in vitro fertilisation (very low certainty).

1 finding from 1 review

In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction 2018 · Cochrane Headline outcomes only
OR 3.1 [1.06, 9]
2 studies · 71 participants
Very low

In vitro maturation vs in vitro fertilisation

Ovarian hyperstimulation syndrome incidence · subfertile women with polycystic ovarian syndrome undergoing assisted reproduction

1 finding from 1 review

In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

LNG‐IUS vs medroxyprogesterone (MPA) 10 mg

Regression rate at 6 months · women with atypical endometrial hyperplasia

It is very uncertain whether levonorgestrel‐releasing intrauterine system (LNG‐IUS) changes regression rate at 6 months compared with medroxyprogesterone (MPA) 10 mg (very low certainty).

1 finding from 1 review

Oral and intrauterine progestogens for atypical endometrial hyperplasia 2018 · Cochrane Headline outcomes only
OR 2.76 [0.26, 29.73]
1 study · 19 participants
Very low

LNG‐IUS vs medroxyprogesterone (MPA) 10 mg

Nausea · women with atypical endometrial hyperplasia

It is very uncertain whether levonorgestrel‐releasing intrauterine system (LNG‐IUS) changes nausea over 6‐month compared with medroxyprogesterone (MPA) 10 mg (very low certainty).

1 finding from 1 review

Oral and intrauterine progestogens for atypical endometrial hyperplasia 2018 · Cochrane Headline outcomes only
OR 0.58 [0.28, 1.18]
1 study · 153 participants
Very low

LNG‐IUS vs medroxyprogesterone (MPA) 10 mg

Vaginal bleeding over 6‐month · women with atypical endometrial hyperplasia

Levonorgestrel‐releasing intrauterine system (LNG‐IUS) may leads to higher vaginal bleeding over 6‐month compared with medroxyprogesterone (MPA) 10 mg (low certainty).

1 finding from 1 review

Oral and intrauterine progestogens for atypical endometrial hyperplasia 2018 · Cochrane Headline outcomes only
OR 2.89 [1.11, 7.52]
1 study · 153 participants
Low

Operative hysteroscopy vs control

Live birth · women with submucous fibroids and otherwise unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Adverse events: hysteroscopy complications · women with submucous fibroids and otherwise unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Clinical pregnancya Ultrasound 12 months · women with submucous fibroids and otherwise unexplained subfertility

It is very uncertain whether operative hysteroscopy changes clinical pregnancya Ultrasound 12 months compared with control (very low certainty).

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
OR 2.44 [0.97, 6.17]
1 study · 94 participants
Very low

Operative hysteroscopy vs control

Adverse events: miscarriaged Ultrasound 12 months · women with submucous fibroids and otherwise unexplained subfertility

It is very uncertain whether operative hysteroscopy changes adverse events: miscarriaged Ultrasound 12 months compared with control (very low certainty).

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
OR 1.54 [0.47, 5]
1 study · 94 participants
Very low

Operative hysteroscopy vs control

Live birth · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Adverse events: hysteroscopy complications · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Operative hysteroscopy vs control

Clinical pregnancya Ultrasound 4 intrauterine insemination cycles · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

Operative hysteroscopy may leads to higher clinical pregnancya Ultrasound 4 intrauterine insemination cycles compared with control (low certainty).

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
OR 4.41 [2.45, 7.96]
1 study · 204 participants
Low

Operative hysteroscopy vs control

Adverse events ‐ Miscarriage · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

The review found no eligible studies for this question.

1 finding from 1 review

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vasodilator vs placebo or no treatment

Live birth · women undergoing fertility treatment

Vasodilator showed no clear difference in live birth compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
RR 1.18 [0.83, 1.69]
3 studies · 350 participants
Moderate

Vasodilator vs placebo or no treatment

Vasodilator side effects · women undergoing fertility treatment

Vasodilator probably leads to higher vasodilator side effects compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
RR 2.35 [1.51, 3.66]
4 studies · 418 participants
Moderate

Vasodilator vs placebo or no treatment

Clinical pregnancy · women undergoing fertility treatment

Vasodilator may leads to higher clinical pregnancy compared with placebo or no treatment (low certainty).

1 finding from 1 review

Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
RR 1.45 [1.19, 1.77]
11 studies · 1054 participants
Low