Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,234 questions · 2,325 findings · 216 reviews · Airways

No studies found 249 · 10.7%GRADE not reported 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Pharmacological treatment vs placebo

Prolonged abstinence at longest · smokers with COPD

Pharmacological treatment leads to higher prolonged abstinence at longest compared with placebo (high certainty).

5 findings from 1 review
Show 2 more findings

Intervention not reported

Change in Exercise Capacity (6MWD) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)
1 finding from 1 review

Intervention not reported

Mortality · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in mortality (low certainty).

1 finding from 1 review

Intervention not reported

Improvement in WHO Functional Class · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in improvement in WHO Functional Class (low certainty).

1 finding from 1 review

Intervention not reported

Serious Adverse Events (Participants with one or more event) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

It is very uncertain whether the intervention changes serious Adverse Events (Participants with one or more event) (very low certainty).

1 finding from 1 review