Cochrane · systematic review · CD011050

Intravenous magnesium sulfate for treating children with acute asthma in the emergency department

Griffiths, B, Kew, KM · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

MgSO4 compared to placebo for treating children with acute asthma in the emergency department

Population: children with acute asthma in the emergency department
4 questions
OutcomeEffectEvidenceStatus / GRADE
Hospital admissions
MgSO4 vs placebo
OR 0.32 [0.14, 0.74]3 studies · 115 participantsLow
Downgraded: imprecision, inconsistency
ED treatment time (minutes)
MgSO4 vs placebo
no estimate extracted1 study · 27 participantsLow
Downgraded: imprecision
Return to ED within 48 hours
MgSO4 vs placebo
OR 0.4 [0.02, 10.3]2 studies · 85 participantsLow
Downgraded: imprecision
Hospital length of stay (hours)
MgSO4 vs placebo
no estimate extracted1 study · 47 participantsLow
Downgraded: imprecision, publication bias