Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Neuroprotection vs control

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes visual field: the proportion of participants with progression of… compared with control (very low certainty).

1 finding from 1 review

Neuroprotection vs control

Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection vs control

Adverse effects: ocular allergy to the study medication requiring discontinuation up to 4 years' · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes adverse effects: ocular allergy to the study medication requiring… compared with control (very low certainty).

1 finding from 1 review

Immediate cataract surgery vs delayed cataract surgery

Development of choroidal neovascularization · people with cataract and age‐related macular degeneration

It is very uncertain whether immediate cataract surgery changes development of choroidal neovascularization compared with delayed cataract surgery (very low certainty).

1 finding from 1 review