Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,497 questions · 1,590 findings · 129 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 281 · 17.7%GRADE not reported 74 · 4.7%Very low 410 · 25.8%Low 420 · 26.4%Moderate 280 · 17.6%High 125 · 7.9%

Platin‐based maintenance chemotherapy vs observation

Progression‐free survival · patients with epithelial ovarian cancer

Platin‐based maintenance chemotherapy showed no clear difference in 3‐year PFS compared with observation (moderate certainty).

3 findings from 1 review

Interferon + chemotherapy vs chemotherapy alone

Adverse event (flu‐like symptoms) · Women with advanced (Stage II‐IV) epithelial ovarian cancer who have undergone surgery

Interferon + chemotherapy showed no clear difference in adverse event (flu‐like symptoms) compared with chemotherapy alone (low certainty).

1 finding from 1 review

Dietary modifications (counselling or dietary change) vs no nutritional intervention

Diarrhoea · People undergoing RT for pelvic cancer

Dietary modification probably leads to lower diarrhoea at end of treatment compared with no nutritional intervention (moderate certainty).

1 finding from 1 review