What do systematic reviews say?

Shengmai vs placebo

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 80 participants
  Low

Shengmai vs placebo

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 106 participants
  GRADE not reported

Shengmai plus usual treatment vs usual treatment alone

Shengmai plus usual treatment may leads to lower lack of improvement in heart failure (NYHA class improved < I class… compared with usual treatment alone (low certainty).

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  RR 0.37 [0.26, 0.51]
  10 studies · 672 participants
  Low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 4 participants
  GRADE not reported

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 354 participants
  Very low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 360 participants
  Very low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 240 participants
  Very low

Shengmai plus usual treatment vs usual treatment alone

• Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 160 participants
  Very low

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in combined outcome of non‐fatal myocardial infarction, non‐fatal… compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.93 [0.81, 1.06]
  11 studies · 9625 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in death from all causes compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.9 [0.7, 1.14]
  12 studies · 9733 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in fatal and non‐fatal myocardial infarction or reinfarction compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.91 [0.77, 1.06]
  10 studies · 9537 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in fatal and non‐fatal stroke compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.72 [0.45, 1.16]
  7 studies · 8536 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins probably leads to lower unstable angina compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.76 [0.59, 0.96]
  9 studies · 8770 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in acute heart failure compared with control at 4 months (3 to 6 months) (moderate certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 0.86 [0.65, 1.15]
  2 studies · 7583 participants
  Moderate

Statins vs Control at 4 months (3 ‐ 6 months)

Statins showed no clear difference in rhabdomyolysis compared with control at 4 months (3 to 6 months) (low certainty).

• Statins for acute coronary syndrome 2014 · Cochrane Headline outcomes only
  RR 6.9 [0.36, 133.47]
  1 study · 4497 participants
  Low

Pre‐hospital vs in‐hospital thrombolysis

Pre‐hospital showed no clear difference in all‐cause hospital mortality compared with in‐hospital thrombolysis (low certainty).

• Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
  RR 0.73 [0.37, 1.41]
  3 studies · 538 participants
  Low

Pre‐hospital vs in‐hospital thrombolysis

• Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 438 participants
  High

Pre‐hospital vs in‐hospital thrombolysis

• Pre‐hospital versus in‐hospital thrombolysis for ST‐elevation myocardial infarction 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 416 participants
  Low