What do systematic reviews say?

Antiplatelet agent vs placebo

Antiplatelet agent showed no clear difference in ipsilateral major or disabling stroke (CT scan or MRI) compared with placebo (low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 1.08 [0.47, 2.47]
  1 study · 372 participants
  Low

Lipid‐lowering agent vs placebo or no treatment

The review found no eligible studies for this question.

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lipid‐lowering agent vs placebo or no treatment

Lipid‐lowering agent showed no clear difference in adverse events (only reported for two studies: one study used CT… compared with placebo or no treatment (low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 0.76 [0.53, 1.1]
  7 studies · 3726 participants
  Low

Lipid‐lowering agent vs placebo or no treatment

The review found no eligible studies for this question.

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antiplatelet agent vs placebo

Antiplatelet agent showed no clear difference in stroke‐related mortality (CT scan or MRI) compared with placebo (low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 1.4 [0.54, 3.59]
  1 study · 372 participants
  Low

Antiplatelet agent vs placebo

It is very uncertain whether antiplatelet agent changes major bleeding (not reported) compared with placebo (very low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 0.98 [0.06, 15.53]
  1 study · 372 participants
  Very low

Antiplatelet agent vs placebo

Antiplatelet agent showed no clear difference in progression of carotid stenosis (DUS/every 6 months) compared with placebo (low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 1.16 [0.79, 1.71]
  1 study · 372 participants
  Low

Antiplatelet agent vs placebo

Antiplatelet agent showed no clear difference in adverse events (not reported) compared with placebo (low certainty).

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  RR 0.81 [0.41, 1.59]
  1 study · 372 participants
  Low

Antiplatelet agent vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antihypertensive agent vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 283 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 112 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  22 studies · 917 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  19 studies · 535 participants
  Low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 111 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 378 participants
  Low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 466 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 410 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 383 participants
  Very low