Findings

What do systematic reviews say?

996 questions · 1,049 findings · 79 reviews · Dementia and Cognitive Improvement

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No studies found 240 · 22.9%GRADE not reported 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Quality of life: psychological (care partner self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 437 participants
Moderate

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Functional ability in targeted activities: personal goals ‐ performance (informant report of participant) · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 476 participants
High

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Functional ability · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 673 participants
Low

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Self‐efficacy · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 456 participants
High

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Mood: depression (participant self‐report) · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 502 participants
Very low

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

QoL · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 853 participants
Moderate

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Quality of life: psychological (care partner self‐report) · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 464 participants
Moderate

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Functional ability in targeted activities: personal goals ‐ performance (participant self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 432 participants
High

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Functional ability in targeted activities: personal goals ‐ performance (informant report of participant) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 446 participants
High

Intervention not reported

Incident clinical dementia Â

1 finding from 1 review

Multi‐domain prognostic models used in middle‐aged adults without known cognitive impairment for predicting subsequent… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 24147 participants
Very low

Intervention not reported

Dementia or cognitive impairmentcÂ

1 finding from 1 review

Multi‐domain prognostic models used in middle‐aged adults without known cognitive impairment for predicting subsequent… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 8565 participants
Very low

Anticholinergic burden reduction interventions vs usual care

Cognitive decline · older adults with and without prior cognitive impairment

1 finding from 1 review

Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 299 participants
Very low

Anticholinergic burden reduction interventions vs usual care

Incidence of dementia · older adults with and without prior cognitive impairment

1 finding from 1 review

Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Anticholinergic burden reduction interventions vs usual care

Adverse effects · older adults with and without prior cognitive impairment

1 finding from 1 review

Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT vs treatment

Depressive symptoms · depression and anxiety for people with dementia and MCI

CBT treatments showed no clear difference in depressive symptoms post‐treatment compared with treatment (moderate certainty).

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
SMD 0.23
13 studies · 893 participants
Moderate

Supportive and counselling interventions vs treatment

Anxiety · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Supportive and counselling interventions vs treatment

Quality of life post‐treatment · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 935 participants
Moderate

Supportive and counselling interventions vs treatment

Activities of daily living · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 511 participants
Very low

Supportive and counselling interventions vs treatment

Cognitive function · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 730 participants
Low

Supportive and counselling interventions vs treatment

Neuropsychiatric symptoms · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 538 participants
Very low