What do systematic reviews say?

Fluid instillation vs no fluid instillation

Fluid instillation probably leads to lower incidence of STP at 24 hours post‐operatively compared with no fluid instillation (moderate certainty).

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  OR 0.38 [0.22, 0.66]
  2 studies · 220 participants
  Moderate

Fluid instillation vs no fluid instillation

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 205 participants
  Moderate

Fluid instillation vs no fluid instillation

The review found no eligible studies for this question.

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fluid instillation vs no fluid instillation

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 205 participants
  Low

Intraperitoneal drain vs no intraperitoneal drain

Intraperitoneal drain may leads to lower incidence of STP at 24 hours post‐operatively compared with no intraperitoneal drain (low certainty).

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  OR 0.3 [0.2, 0.46]
  3 studies · 417 participants
  Low

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

TLS with conventional morphological assessment of still TLS images showed no clear difference in live birth or ongoing pregnancy compared with conventional incubation and assessment (low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.91 [0.67, 1.23]
  3 studies · 826 participants
  Low

TLS utilising embryo selection software vs conventional incubation and assessment

It is very uncertain whether TLS utilising embryo selection software changes miscarriage compared with conventional incubation and assessment (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.63 [0.45, 0.89]
  3 studies · 1617 participants
  Very low

TLS utilising embryo selection software vs conventional incubation and assessment

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 600 participants
  GRADE not reported

TLS utilising embryo selection software vs conventional incubation and assessment

It is very uncertain whether TLS utilising embryo selection software changes clinical pregnancy compared with conventional incubation and assessment (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.95 [0.78, 1.16]
  3 studies · 1617 participants
  Very low

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

TLS with conventional morphological assessment of still TLS images showed no clear difference in miscarriage compared with conventional incubation and assessment (low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1.9 [0.99, 3.61]
  3 studies · 826 participants
  Low

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

TLS with conventional morphological assessment of still TLS images showed no clear difference in stillbirth compared with conventional incubation and assessment (low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1 [0.13, 7.49]
  1 study · 76 participants
  Low

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

TLS with conventional morphological assessment of still TLS images showed no clear difference in clinical pregnancy compared with conventional incubation and assessment (low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1.06 [0.79, 1.41]
  4 studies · 875 participants
  Low

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

It is very uncertain whether TLS utilising embryo selection software changes live birth or ongoing pregnancy compared with TLS with conventional morphological assessment of still TLS images (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.61 [0.32, 1.2]
  1 study · 163 participants
  Very low

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

It is very uncertain whether TLS utilising embryo selection software changes miscarriage compared with TLS with conventional morphological assessment of still TLS images (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1.39 [0.64, 3.01]
  2 studies · 463 participants
  Very low

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

The review found no eligible studies for this question.

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

It is very uncertain whether TLS utilising embryo selection software changes clinical pregnancy compared with TLS with conventional morphological assessment of still TLS images (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.97 [0.67, 1.42]
  2 studies · 463 participants
  Very low

TLS utilising embryo selection software vs conventional incubation and assessment

It is very uncertain whether TLS utilising embryo selection software changes live birth or ongoing pregnancy compared with conventional incubation and assessment (very low certainty).

• Time‐lapse systems for embryo incubation and assessment in assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1.12 [0.92, 1.36]
  3 studies · 1617 participants
  Very low

37°C vs any lower temperature

• Temperature of embryo culture for assisted reproduction 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  GRADE not reported

37°C vs any lower temperature

It is very uncertain whether 37°C changes miscarriage compared with any lower temperature (very low certainty).

• Temperature of embryo culture for assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.9 [0.52, 1.55]
  1 study · 412 participants
  Very low

37°C vs any lower temperature

It is very uncertain whether 37°C changes clinical pregnancy compared with any lower temperature (very low certainty).

• Temperature of embryo culture for assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 1.08 [0.73, 1.6]
  1 study · 412 participants
  Very low