Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

External uterine compression (all methods) plus normal care vs normal care

Side effects of the intervention (e.g. trauma, necrosis) ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)

Mortality due to bleeding ‐ not reported · treating primary postpartum haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)

Hysterectomy to control bleeding · treating primary postpartum haemorrhage

It is very uncertain whether one uterine devascularisation technique (uterine arterial… changes hysterectomy to control bleeding compared with another uterine devascularisation technique (surgical… (very low certainty).

1 finding from 1 review

Additional support vs usual care

Satisfaction with pregnancy care Pregnancy care rated as "very helpful" · women at increased risk of low birthweight babies (maternal outcomes)

Additional support probably leads to higher satisfaction with pregnancy care Pregnancy care rated as "very… compared with usual care during pregnancy (moderate certainty).

1 finding from 1 review

Additional support vs usual care

Death of a baby (stillbirth or neonatal death) report of perinatal death · women at increased risk of low birthweight babies (maternal outcomes)

Additional support showed no clear difference in stillbirth/neonatal death compared with usual care during pregnancy (low certainty).

1 finding from 1 review

Additional support vs usual care

Number of antenatal hospital admissions · women at increased risk of low birthweight babies (maternal outcomes)

Additional support probably leads to lower antenatal hospital admissions Number of admissions per woman compared with usual care during pregnancy (moderate certainty).

2 findings from 1 review

Additional support vs usual care

Postnatal depression · women at increased risk of low birthweight babies (maternal outcomes)

Additional support showed no clear difference in postnatal depression Self‐reported compared with usual care during pregnancy (low certainty).

2 findings from 1 review

Oxytocin vs ergot alkaloids

Diastolic blood pressure > 100 mm Hg between delivery of the baby and discharge from the labour ward · women in the third stage of labour

Oxytocin showed no clear difference in diastolic blood pressure > 100 mm Hg between delivery of the baby… compared with ergot alkaloids (low certainty).

1 finding from 1 review