What do systematic reviews say?

Zeta sperm selection vs ICSI

It is very uncertain whether zeta sperm selection changes miscarriage per woman randomly assigned compared with ICSI (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  OR 0.73 [0.16, 3.37]
  1 study · 203 participants
  Very low

Zeta sperm selection vs ICSI

It is very uncertain whether zeta sperm selection changes miscarriage per clinical pregnancy compared with ICSI (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 0.41 [0.1, 1.68]
  1 study · 62 participants
  Very low

Zeta sperm selection vs ICSI

It is very uncertain whether zeta sperm selection changes clinical pregnancy per woman randomly assigned compared with ICSI (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.82 [1.2, 2.75]
  1 study · 203 participants
  Very low

Magnetic‐activated cell sorting (MACS) vs hyaluronic acid‐selected sperm (HA‐ICSI)

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes miscarriage per woman randomly assigned compared with hyaluronic acid‐selected sperm (HA‐ICSI) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.52 [0.1, 23.35]
  1 study · 78 participants
  Very low

Magnetic‐activated cell sorting (MACS) vs hyaluronic acid‐selected sperm (HA‐ICSI)

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes miscarriage per clinical pregnancy compared with hyaluronic acid‐selected sperm (HA‐ICSI) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.06 [0.07, 15.64]
  1 study · 37 participants
  Very low

Magnetic‐activated cell sorting (MACS) vs hyaluronic acid‐selected sperm (HA‐ICSI)

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes clinical pregnancy per woman randomly assigned compared with hyaluronic acid‐selected sperm (HA‐ICSI) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.44 [0.91, 2.27]
  1 study · 78 participants
  Very low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs ICSI

Hyaluronic acid‐selected sperm (HA‐ICSI) may leads to lower miscarriage per woman randomly assigned compared with ICSI (low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 0.61 [0.45, 0.83]
  3 studies · 3005 participants
  Low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs ICSI

Hyaluronic acid‐selected sperm (HA‐ICSI) may leads to lower miscarriage per clinical pregnancy compared with ICSI (low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 0.62 [0.46, 0.82]
  3 studies · 1065 participants
  Low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs ICSI

Hyaluronic acid‐selected sperm (HA‐ICSI) showed no clear difference in clinical pregnancy per woman randomly assigned compared with ICSI (low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1 [0.92, 1.09]
  4 studies · 3492 participants
  Low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes live birth per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.13 [0.64, 2.01]
  1 study · 100 participants
  Very low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes miscarriage per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 0.8 [0.23, 2.81]
  1 study · 100 participants
  Very low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes miscarriage per clinical pregnancy compared with viscous medium containing HA (SpermSlow) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 0.76 [0.24, 2.44]
  1 study · 41 participants
  Very low

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes clinical pregnancy per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.05 [0.66, 1.68]
  1 study · 100 participants
  Very low

Magnetic‐activated cell sorting (MACS) vs ICSI

It is very uncertain whether magnetic‐activated cell sorting (MACS) changes live birth per woman randomly assigned compared with ICSI (very low certainty).

• Advanced sperm selection techniques for assisted reproduction 2019 · Cochrane Headline outcomes only
  RR 1.95 [0.89, 4.29]
  1 study · 62 participants
  Very low

Thyroxine vs placebo or no treatment

Thyroxine showed no clear difference in live birth rate – euthyroid women with anti‐TPO antibodies compared with placebo or no treatment (low certainty).

• Thyroxine replacement for subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism 2019 · Cochrane Headline outcomes only
  RR 1.04 [0.83, 1.29]
  2 studies · 686 participants
  Low

Thyroxine vs placebo or no treatment

Thyroxine led to lower adverse events including maternal pregnancy complications, foetal… compared with placebo or no treatment; GRADE not reported.

• Thyroxine replacement for subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 1 participants
  GRADE not reported

Thyroxine vs placebo or no treatment

Thyroxine showed no clear difference in miscarriage – anti‐TPO antibodies compared with placebo or no treatment (low certainty).

• Thyroxine replacement for subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism 2019 · Cochrane Headline outcomes only
  RR 0.83 [0.47, 1.46]
  2 studies · 686 participants
  Low

Specific technique vs standard techniques

Specific technique showed no clear difference in incidence of STP at 24 hours post‐operatively compared with standard technique (low certainty).

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  OR 0.87 [0.41, 1.82]
  1 study · 118 participants
  Low

Intraperitoneal drain vs no intraperitoneal drain

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 320 participants
  Very low

Intraperitoneal drain vs no intraperitoneal drain

The review found no eligible studies for this question.

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found