Findings

What do systematic reviews say?

1,562 questions · 1,645 findings · 107 reviews · Wounds

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No studies found 651 · 39.6%GRADE not reported 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

High frequency ultrasound vs no ultrasound

Costs · people with venous leg ulcers

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 337 participants
Moderate

Low frequency ultrasound vs no ultrasound

Ulcers completely healed · venous leg ulcers

It is very uncertain whether low frequency ultrasound changes proportion of ulcers completely healed at 8 to 12 weeks compared with no ultrasound (very low certainty).

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
RR 3.91 [0.47, 32.85]
2 studies · 61 participants
Very low

Low frequency ultrasound vs no ultrasound

Adverse events · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low frequency ultrasound vs no ultrasound

Health‐related quality of life · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low frequency ultrasound vs no ultrasound

Costs · venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High frequency ultrasound vs no ultrasound

Healing - 1 year · people with venous leg ulcers

High frequency ultrasound showed no clear difference in healing at 12 months (nurse‐reported data) compared with no ultrasound (low certainty).

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
RR 0.93 [0.73, 1.18]
1 study · 337 participants
Low

High frequency ultrasound vs no ultrasound

Change in ulcer size · people with venous leg ulcers

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 165 participants
Very low

High frequency ultrasound vs no ultrasound

Non‐serious adverse events · people with venous leg ulcers

High frequency ultrasound probably leads to higher non‐serious adverse events compared with no ultrasound (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
RR 1.29 [1.02, 1.64]
1 study · 337 participants
Moderate

High frequency ultrasound vs no ultrasound

Serious adverse events · people with venous leg ulcers

High frequency ultrasound showed no clear difference in serious adverse events compared with no ultrasound (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
RR 1.21 [0.78, 1.89]
1 study · 337 participants
Moderate

High frequency ultrasound vs no ultrasound

HRQoL: 12‐week SF‐12 mean Physical/Mental Component Scores scale from 0 to 100 · people with venous leg ulcers

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 285 participants
Moderate

High frequency ultrasound vs no ultrasound

HRQoL at 6 or 12 months · people with venous leg ulcers

1 finding from 1 review

Therapeutic ultrasound for venous leg ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 229 participants
Moderate

Scalpel vs electrosurgery

Wound infection · people undergoing surgery involving major abdominal incisions

Scalpel showed no clear difference in wound infection compared with electrosurgery (low certainty).

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
RR 1.07 [0.74, 1.54]
11 studies · 2178 participants
Low

Scalpel vs electrosurgery

Time to complete healing · people undergoing surgery involving major abdominal incisions

The review found no eligible studies for this question.

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Scalpel vs electrosurgery

Wound dehiscence · people undergoing surgery involving major abdominal incisions

It is very uncertain whether scalpel changes wound dehiscence compared with electrosurgery (very low certainty).

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
RR 1.21
6 studies · 1064 participants
Very low

Scalpel vs electrosurgery

Postoperative pain · people undergoing surgery involving major abdominal incisions

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 949 participants
GRADE not reported

Scalpel vs electrosurgery

Wound incision time (seconds) · people undergoing surgery involving major abdominal incisions

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 325 participants
Moderate

Scalpel vs electrosurgery

Wound‐related blood loss (mL) · people undergoing surgery involving major abdominal incisions

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 241 participants
Moderate

Scalpel vs electrosurgery

Adhesion or scar formation · people undergoing surgery involving major abdominal incisions

1 finding from 1 review

Scalpel versus electrosurgery for major abdominal incisions 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
GRADE not reported

Topical phenytoin vs hydrocolloid dressing

Time to complete healing · people with pressure ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical phenytoin for treating pressure ulcers 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical phenytoin vs simple dressing

The proportion of pressure ulcers healed · people with pressure ulcers

It is very uncertain whether topical phenytoin group changes proportion of ulcers healed within trial period (eight weeks) compared with a simple dressing (very low certainty).

1 finding from 1 review

Topical phenytoin for treating pressure ulcers 2017 · Cochrane Headline outcomes only
RR 1.33 [0.63, 2.78]
1 study · 55 participants
Very low