Findings

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Cyanoacrylate vs band ligation

Mortality Total of deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes mortality Total of deaths and the end of compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Re‐bleeding Bleeding after initial success in the intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes re‐bleeding Bleeding after initial success in the intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes control of bleeding Success in control the active variceal bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate vs alcohol

Re‐bleeding Re‐bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes re‐bleeding Re‐bleeding after intervention compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs alcohol

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in controlling the active variceal… compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Re‐bleeding Re‐bleeding after the bleeding was controlled in the first intervention · acute bleeding gastric varices in people with portal hypertension

Cyanoacrylate may leads to lower re‐bleeding Re‐bleeding after the bleeding was controlled in the… compared with band ligation (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Complications (general) Number of total complications · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes complications (general) Number of total complications compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in control variceal bleeding compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Total mortality Total deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes total mortality Total deaths and the end of compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

day ‐ mortality Mortality due to bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes day ‐ mortality Mortality due to bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Failure of intervention Continuous bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes failure of intervention Continuous bleeding after intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Complications (fever) Presence of fever · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes complications (fever) Presence of fever compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Intervention not reported

Mortality · patients with hepatic encephalopathy.

The intervention showed no clear difference in mortality (low certainty).

1 finding from 1 review

Intervention not reported

Hepatic encephalopathy · patients with hepatic encephalopathy.

The intervention showed no clear difference in hepatic encephalopathy (low certainty).

1 finding from 1 review

Peginterferon plus ribavirin vs non‐pegylated interferon plus ribavirin

All‐cause mortality or liver‐related morbidity · people with chronic hepatitis C

Peginterferon plus ribavirin showed no clear difference in liver‐related morbidity plus all‐cause mortality compared with non‐pegylated interferon plus ribavirin (low certainty).

1 finding from 1 review