Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Women not using/receiving misoprostol at birth · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes women not using/receiving misoprostol at birth compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Inappropriate use (or misuse) of misoprostol · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes inappropriate use (or misuse) of misoprostol compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

Maternal transfer or referral to a health facility · women in the third stage of labour

It is very uncertain whether advance misoprostol distribution/provision to pregnant women for… changes maternal transfer or referral to a health facility compared with usual (or standard) care (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Composite outcome: symptoms of leg cramps (intensity and frequency) Complete recovery: no leg cramps after treatment · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).

1 finding from 1 review