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What do systematic reviews say?

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Evidence found and GRADE certainty

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

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No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Health‐related quality of life · patients with LADA

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health service utilisation and costs · patients with LADA

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings: insulin detemir vs Insulin glargin (control)

Percentage of participants having at least one severe hypoglycaemic event · patients with type 2 diabetes mellitus

Insulin detemir (intervention) showed no clear difference in percentage of participants having at least one severe hypoglycaemic… compared with insulin glargin (control) (low certainty).

1 finding from 1 review

Summary of findings: insulin detemir vs Insulin glargin (control)

Percentage of participants having at least one hypoglycaemic event · patients with type 2 diabetes mellitus

Insulin detemir (intervention) showed no clear difference in percentage of participants having at least one hypoglycaemic event compared with insulin glargin (control) (low certainty).

1 finding from 1 review

Summary of findings: insulin detemir vs Insulin glargin (control)

Injection‐site reaction Rates of patients · patients with type 2 diabetes mellitus

Insulin detemir (intervention) may leads to higher percentage of participants having at least one injection site reaction compared with insulin glargin (control) (low certainty).

1 finding from 1 review