Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,281 questions · 1,361 findings · 120 reviews · Developmental, Psychosocial and Learning Problems

No studies found 286 · 21%GRADE not reported 61 · 4.5%Very low 381 · 28%Low 381 · 28%Moderate 228 · 16.8%High 24 · 1.8%

Herbal agents vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · patients with infantile colic

Herbal agents may leads to higher reduction in crying duration Difference before and after treatment… compared with placebo (low certainty).

1 finding from 1 review

Herbal agents vs placebo

Responders Number of infants who improved after treatment · patients with infantile colic

Herbal agents probably leads to higher responders Number of infants who improved after treatment compared with placebo (moderate certainty).

1 finding from 1 review

Sugar vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether sugar changes reduction in crying duration Difference before and after treatment… compared with placebo (very low certainty).

1 finding from 1 review

Cimetropium bromide vs placebo

Reduction in crying duration Difference between final values (minutes per crisis of crying) · infants with colic defined by recognised criteria

It is very uncertain whether cimetropium bromide changes reduction in crying duration Difference between final values… compared with placebo (very low certainty).

1 finding from 1 review

Cimetropium bromide vs placebo

Responders Number of infants who improved after treatment · infants with colic defined by recognised criteria

It is very uncertain whether cimetropium bromide changes responders Number of infants who improved after treatment compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Protective behaviours (self protective events measured using a stranger simulation test immediately post intervention) · children (aged 5 to 12) and adolescents (aged 13 to 18)

The intervention probably leads to higher protective behaviours (self protective events measured using a… (moderate certainty).

1 finding from 1 review

Intervention not reported

Questionnaire‐based knowledge (factual knowledge measured by assessing responses to items on a questionnaire or multi‐choice test, immediately post intervention) (higher score = higher knowledge) · children (aged 5 to 12) and adolescents (aged 13 to 18)
1 finding from 1 review

Intervention not reported

Vignette‐based knowledge (applied knowledge measured by assessing responses to hypothetical scenarios, immediately post intervention) (higher score = higher knowledge) · children (aged 5 to 12) and adolescents (aged 13 to 18)
1 finding from 1 review

Intervention not reported

Disclosures (of past or current child sexual abuse made during or after programme completion) · children (aged 5 to 12) and adolescents (aged 13 to 18)

The intervention probably leads to higher disclosures (of past or current child sexual abuse made during or… (moderate certainty).

1 finding from 1 review

Intensive advocacy interventions for women who experience intimate partner abuse vs (Optimised) usual care

Physical abuse (dichotomous outcome) · women with intimate partner abuse

It is very uncertain whether intensive advocacy interventions for women who experience intimate… changes physical abuse (dichotomous outcome) compared with usual care at up to 12‐month follow‐up (very low certainty).

1 finding from 1 review