Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,187 questions · 1,248 findings · 108 reviews · Stroke

No studies found 275 · 22%GRADE not reported 56 · 4.5%Very low 269 · 21.6%Low 349 · 28%Moderate 216 · 17.3%High 83 · 6.7%

Cilostazol vs aspirin

Intracerebral haemorrhage (ICH) · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in intracerebral haemorrhage (ICH) compared with aspirin (low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting short‐term prophylactic dose anticoagulation vs avoiding anticoagulation

Death · survivors of stroke due to intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Starting short‐term prophylactic dose… changes death compared with avoiding anticoagulation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting short‐term prophylactic dose anticoagulation vs avoiding anticoagulation

Venous thromboembolism · survivors of stroke due to intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Starting short‐term prophylactic dose… changes venous thromboembolism compared with avoiding anticoagulation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting short‐term prophylactic dose anticoagulation vs avoiding anticoagulation

Intracerebral haemorrhage (ICH) · survivors of stroke due to intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Starting short‐term prophylactic dose… changes intracerebral haemorrhage (ICH) compared with avoiding anticoagulation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting short‐term prophylactic dose anticoagulation vs avoiding anticoagulation

Functional status: mRS 0‐2 · survivors of stroke due to intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Starting short‐term prophylactic dose… changes functional status: mRS 0‐2 compared with avoiding anticoagulation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

MACE · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… probably leads to lower MACE (MACE) compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

Death · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… showed no clear difference in death compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

All major occlusive vascular events · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… probably leads to lower all major occlusive vascular events compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

Intracranial haemorrhage · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… showed no clear difference in intracranial haemorrhage compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death or stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher death or stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Type of recurrent event · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in type of recurrent event compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment may leads to higher death compared with conventional medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Dependency · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in dependency compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review