Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

113 questions · 141 findings · 6 reviews · Esthetic dentistry

No studies found 16 · 11.3%GRADE not reported 64 · 45.4%Very low 54 · 38.3%Low 7 · 5%Moderate 0 · 0%High 0 · 0%

1.5% HP + 0.05% HF mouthwash vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 1.5% HP + 0.05% HF mouthwash changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

18% CP paint-on gel (4x/day) vs 18% CP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 18% CP paint-on gel (4x/day) changes tooth whitening - assessed by the dentist compared with 18% CP paint-on gel (2x/day) (very low certainty).

1 finding from 1 review

14% HP strip vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 14% HP strip changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

2 findings from 1 review

1% STPP chewing gum vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 1% STPP chewing gum changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

6% HP strip vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6% HP strip changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

10% CP gel in tray vs 16% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray changes tooth whitening - assessed by the dentist compared with 16% CP gel in tray (very low certainty).

1 finding from 1 review

10% HP strip vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% HP strip changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

2 findings from 1 review

6% HP paint-on gel vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6% HP paint-on gel changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

10% CP gel in tray + KN + NaF vs 10% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray + KN + NaF changes tooth whitening - assessed by the dentist compared with 10% CP gel in tray (very low certainty).

1 finding from 1 review

SPC paint-on gel vs 18% CP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 19% SPC paint-on gel changes tooth whitening - assessed by the dentist compared with 18% CP paint-on gel (very low certainty).

1 finding from 1 review

A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of anterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of posterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Tactile sensitivity (method a, ordinal scale) · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) led to lower tactile sensitivity (method a, ordinal scale) compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review