What do systematic reviews say?

Intervention not reported

• Compression therapy for treating post‐thrombotic syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Moderate

Intervention not reported

• Compression therapy for treating post‐thrombotic syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Moderate

Intervention not reported

The review found no eligible studies for this question.

• Compression therapy for treating post‐thrombotic syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement showed no clear difference in catheter‐related blood stream infection (during hospitalisation) compared with routine change of peripheral intravenous catheters (low certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 0.61 [0.08, 4.68]
  7 studies · 7323 participants
  Low

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement showed no clear difference in thrombophlebitis (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 1.07 [0.93, 1.25]
  7 studies · 7323 participants
  Moderate

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement showed no clear difference in thrombophlebitis (per device days) (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 0.9 [0.76, 1.08]
  6 studies · 32709 participants
  Moderate

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement showed no clear difference in all‐cause blood stream infection (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 0.47 [0.15, 1.53]
  1 study · 3283 participants
  Moderate

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 4244 participants
  Moderate

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement probably leads to higher infiltration (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 1.16 [1.06, 1.26]
  6 studies · 7123 participants
  Moderate

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Effects of clinically‐indicated replacement probably leads to higher catheter blockage (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

• Clinically‐indicated replacement versus routine replacement of peripheral venous catheters 2019 · Cochrane Headline outcomes only
  RR 1.14 [1.01, 1.29]
  7 studies · 7323 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in primary patency rate at 4 yearsa (moderate certainty).

• Endovascular versus open repair of asymptomatic popliteal artery aneurysm 2019 · Cochrane Headline outcomes only
  RR 1 [0.76, 1.32]
  Studies not reported
  Moderate

Intervention not reported

The intervention showed no clear difference in assisted primary patency rate at 4 years (moderate certainty).

• Endovascular versus open repair of asymptomatic popliteal artery aneurysm 2019 · Cochrane Headline outcomes only
  RR 1 [0.76, 1.32]
  Studies not reported
  Moderate

Intervention not reported

• Endovascular versus open repair of asymptomatic popliteal artery aneurysm 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Intervention not reported

• Endovascular versus open repair of asymptomatic popliteal artery aneurysm 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

TNF‐α blockers intervention vs placebo or additional treatment

TNF‐α blockers intervention may leads to lower treatment resistance compared with placebo or additional treatment (low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 0.57 [0.38, 0.86]
  5 studies · 494 participants
  Low

TNF‐α blockers intervention vs placebo or additional treatment

TNF‐α blockers intervention showed no clear difference in incidence of coronary artery abnormalities compared with placebo or additional treatment (low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 1.18 [0.45, 3.12]
  3 studies · 270 participants
  Low

TNF‐α blockers intervention vs placebo or additional treatment

TNF‐α blockers intervention may leads to lower adverse effects after treatment initiation: infusion reactions compared with placebo or additional treatment (low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 0.06 [0.01, 0.45]
  3 studies · 250 participants
  Low

TNF‐α blockers intervention vs placebo or additional treatment

TNF‐α blockers intervention showed no clear difference in adverse effects after treatment initiation: infections compared with placebo or additional treatment (low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 0.68 [0.33, 1.37]
  2 studies · 227 participants
  Low

TNF‐α blockers intervention vs placebo or additional treatment

It is very uncertain whether TNF‐α blockers intervention changes adverse effects after treatment initiation: cutaneous reactions (rash) compared with placebo or additional treatment (very low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 4.71 [0.24, 90.69]
  1 study · 31 participants
  Very low

TNF‐α blockers intervention vs placebo or additional treatment

It is very uncertain whether TNF‐α blockers intervention changes adverse effects after treatment initiation: cutaneous reactions… compared with placebo or additional treatment (very low certainty).

• TNF‐α blockers for the treatment of Kawasaki disease in children 2019 · Cochrane Headline outcomes only
  RR 0.31 [0.04, 2.68]
  1 study · 31 participants
  Very low