Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,495 questions · 1,554 findings · 140 reviews · Heart

No studies found 272 · 17.5%GRADE not reported 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Intervention not reported

Total cardiovascular mortality · Free‐living adults who were healthy, had established cardiovascular disease or risk factors for cardiovascular disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Fatal and non‐fatal myocardial infarction · Free‐living adults who were healthy, had established cardiovascular disease or risk factors for cardiovascular disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Coronary artery bypass graft surgery · Free‐living adults who were healthy, had established cardiovascular disease or risk factors for cardiovascular disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Percutaneous transluminal coronary angioplasty · Free‐living adults who were healthy, had established cardiovascular disease or risk factors for cardiovascular disease

The review found no eligible studies for this question.

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

Cardiovascular mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in cardiovascular mortality compared with aspirin alone (moderate certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

Fatal or nonfatal myocardial infarction · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin probably leads to lower fatal and non‐fatal myocardial infarction compared with aspirin alone (moderate certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

Fatal and non‐fatal ischaemic stroke · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin probably leads to lower fatal and non‐fatal ischaemic stroke compared with aspirin alone (moderate certainty).

1 finding from 1 review