Findings

What do systematic reviews say?

1,139 questions · 1,173 findings · 89 reviews · Neuromuscular

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No studies found 302 · 25.7%GRADE not reported 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%

Amantadine vs placebo

Fatigue · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Change in activity limitations · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Participation · people with fatigue in Guillain‐Barré syndrome

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
74 participants
Low

Amantadine vs placebo

Health related quality of life after 12 or more weeks or more after commencement of intervention (not reported) · people with fatigue in Guillain‐Barré syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Serious adverse events · people with fatigue in Guillain‐Barré syndrome

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
80 participants
GRADE not reported

Ascorbic acid vs placebo

Reduction in fatigue · people with fatigue in peripheral neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ascorbic acid vs placebo

Fatigue · people with fatigue in peripheral neuropathy

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 404 participants
Moderate

Ascorbic acid vs placebo

Change in activity limitations · people with fatigue in peripheral neuropathy

1 finding from 1 review

Interventions for fatigue in peripheral neuropathy 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 406 participants
GRADE not reported

Endoscopic vs open or mini‐open carpal tunnel release

Symptom Severity Scale (Levine) at 3 months or less Participants' self assessment questionnaire. Scale from: 1 to 5. · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 551 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Minor complications (3 to 6 weeks · carpal tunnel syndrome

Endoscopic may leads to lower minor complications events with minor complications compared with open or mini‐open carpal tunnel release (low certainty).

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
RR 0.55 [0.38, 0.81]
18 studies · 1786 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Functional ability · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 551 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Grip strength at 3 months or less Dynamometer · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 560 participants
Moderate

Endoscopic vs open or mini‐open carpal tunnel release

Overall improvement at more than 3 months Participants' subjective evaluation · carpal tunnel syndrome

Endoscopic showed no clear difference in overall improvement at more than 3 months Participants' subjective… compared with open or mini‐open carpal tunnel release (low certainty).

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
RR 1.04 [0.95, 1.14]
4 studies · 317 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Symptom Severity Scale (Levine) at more than 3 months Participants' self assessment questionnaire. Scale from: 1 to 5. · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 273 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Function Status Scale (Levine) at more than 3 months Participants' self assessment questionnaire. Scale from: 1 to 5. · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 273 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Grip strength ‐ Vitamin D · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 56 participants
Low

Endoscopic vs open or mini‐open carpal tunnel release

Return to previous activities ‐ Resumption of work (days) · carpal tunnel syndrome

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 274 participants
Very low

Endoscopic vs open or mini‐open carpal tunnel release

Major complications · carpal tunnel syndrome

Endoscopic showed no clear difference in major complications (events) compared with open or mini‐open carpal tunnel release (low certainty).

1 finding from 1 review

Endoscopic release for carpal tunnel syndrome 2014 · Cochrane Headline outcomes only
RR 1 [0.38, 2.64]
15 studies · 1508 participants
Low

Hydroxytryptophan vs placebo

Short‐term (within 1 month) percentage change (improvement) in overall speech production · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Thyrotropin‐releasing hormone tartrate vs placebo

Short‐term (1 week) change in quality of life scores related to communication as measured by validated communication assessments · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported