Weight (kg) · people with or without existing cardiovascular disease, men and women
1 finding from 1 review
Intervention not reported
Major adverse cardiovascular events (MACE) · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention probably leads to lower major adverse cardiovascular events (MACE) (moderate certainty).
1 finding from 1 review
Intervention not reported
All‐cause mortality · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention showed no clear difference in all‐cause mortality (high certainty).
1 finding from 1 review
Intervention not reported
Myocardial infarction (non‐fatal) · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention probably leads to lower myocardial infarction (non‐fatal) (moderate certainty).
1 finding from 1 review
Intervention not reported
Stroke (non‐fatal) · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention probably leads to lower stroke (non‐fatal) (moderate certainty).
1 finding from 1 review
Intervention not reported
Cardiovascular mortality · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention showed no clear difference in cardiovascular mortality (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ hepatopathy · people with cardiovascular disease or at high risk of cardiovascular disease
The intervention showed no clear difference in adverse events ‐ hepatopathy (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ myopathy · people with cardiovascular disease or at high risk of cardiovascular disease
It is very uncertain whether the intervention changes adverse events ‐ myopathy (very low certainty).
1 finding from 1 review
Outcomes length of · DCM (non‐ischaemic)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality (HR) ‐ main analysisa 16.5 to 67.6 months · DCM (non‐ischaemic)
ICD plus optimal medical therapy leads to lower all‐cause mortality (HR) ‐ main analysisa 16.5 to 67.6 months compared with optimal medical therapy alone (high certainty).
1 finding from 1 review
Cardiovascular mortality · DCM (non‐ischaemic)
ICD plus optimal medical therapy showed no clear difference in cardiovascular mortality (RR)b 22.8 to 67.6 months compared with optimal medical therapy alone (moderate certainty).
1 finding from 1 review
Sudden cardiac death · DCM (non‐ischaemic)
ICD plus optimal medical therapy leads to lower sudden cardiac death (HR)a 24 to 67.6 months compared with optimal medical therapy alone (high certainty).
1 finding from 1 review
Adverse events 67.7 months · DCM (non‐ischaemic)
1 finding from 1 review
Noncardiovascular mortality (RR)b 22.8 to 67.6 months · DCM (non‐ischaemic)
ICD plus optimal medical therapy showed no clear difference in noncardiovascular mortality (RR)b 22.8 to 67.6 months compared with optimal medical therapy alone (moderate certainty).
1 finding from 1 review
Health‐related quality of life 24 to 29 months · DCM (non‐ischaemic)
1 finding from 1 review
First ICD‐related hospitalisation ‐ not reported · DCM (non‐ischaemic)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · patients with stable angina pectoris
It is very uncertain whether exercise‐based cardiac rehabilitation changes all‐cause mortality compared with usual care (very low certainty).
1 finding from 1 review
Acute myocardial infarction · patients with stable angina pectoris
It is very uncertain whether exercise‐based cardiac rehabilitation changes acute myocardial infarction (AMI) compared with usual care (very low certainty).
1 finding from 1 review
Exercise capacity · patients with stable angina pectoris
1 finding from 1 review
Cardiovascular hospital admissions · patients with stable angina pectoris
It is very uncertain whether exercise‐based cardiac rehabilitation changes cardiovascular‐related hospital admissions ( compared with usual care (very low certainty).
1 finding from 1 review