Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,187 questions · 1,248 findings · 108 reviews · Stroke

No studies found 275 · 22%GRADE not reported 56 · 4.5%Very low 269 · 21.6%Low 349 · 28%Moderate 216 · 17.3%High 83 · 6.7%

Endovascular coiling vs neurosurgical clipping

Death or dependence · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling probably leads to lower poor outcome: death or dependence in daily activities (12 months) compared with neurosurgical clipping (moderate certainty).

2 findings from 1 review

Endovascular coiling vs neurosurgical clipping

Death from any cause (12 months) · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling showed no clear difference in death from any cause (12 months) compared with neurosurgical clipping (moderate certainty).

1 finding from 1 review

Endovascular coiling vs neurosurgical clipping

Delayed cerebral ischaemia · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling probably leads to lower delayed cerebral ischaemia (2–3 months) compared with neurosurgical clipping (moderate certainty).

1 finding from 1 review

Endovascular coiling vs neurosurgical clipping

Rebleeding · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling leads to higher rebleeding postprocedure up to 1 year compared with neurosurgical clipping (high certainty).

2 findings from 1 review

Endovascular coiling vs neurosurgical clipping

Complications from the intervention · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling showed no clear difference in complications from the intervention compared with neurosurgical clipping (low certainty).

1 finding from 1 review

Acupuncture vs all control (sham and open)

Death or dependency at end of · people with acute stroke

It is very uncertain whether acupuncture changes death or dependency at end of compared with all control (sham and open) (very low certainty).

2 findings from 1 review

Acupuncture vs sham control

Death or dependency at end of · people with acute stroke

Acupuncture showed no clear difference in death or dependency at end of compared with sham control (low certainty).

2 findings from 1 review

Acupuncture vs sham control

Death or institutional care by the end of · people with acute stroke

Acupuncture may leads to lower death or institutional care at end of compared with sham control (low certainty).

1 finding from 1 review

Acupuncture vs sham control

Death within first 2 weeks · people with acute stroke

Acupuncture showed no clear difference in death within first 2 weeks compared with sham control (low certainty).

1 finding from 1 review

Acupuncture vs sham control

Death during whole · people with acute stroke

Acupuncture showed no clear difference in death during whole compared with sham control (low certainty).

1 finding from 1 review

Acupuncture vs sham control

Adverse events related to acupuncture · people with acute stroke

Acupuncture showed no clear difference in adverse events related to acupuncture compared with sham control (low certainty).

1 finding from 1 review