Findings

What do systematic reviews say?

2,252 questions · 2,353 findings · 210 reviews · Neonatal

Sort:Best matchNewestHighest certainty Download CSV

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Opioids vs phenobarbital

Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 96 participants
Low

Opioids vs Placebo, no intervention or usual care (with or without placebo)

Length of hospital stay · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Opioids vs chlorpromazine

Treatment failure To discharge · newborn infants with opioid withdrawal

Opioid probably leads to lower treatment failure To discharge compared with chlorpromazine (moderate certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 0.08 [0.01, 0.62]
1 study · 90 participants
Moderate

Opioids vs chlorpromazine

Seizures To discharge · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Low

Opioids vs chlorpromazine

Neonatal or infant mortality · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioids vs chlorpromazine

Neurodevelopmental disability · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioids vs chlorpromazine

Length of hospital stay · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioids vs chlorpromazine

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 76 participants
Low

Opioids vs chlorpromazine

Adverse events (treatment related) · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Low

Opioids vs Placebo, no intervention or usual care (with or without placebo)

Days treatment · newborn infants with opioid withdrawal

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Opioids vs Placebo, no intervention or usual care (with or without placebo)

Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Morphine vs methadone

Treatment failure To discharge · newborn infants with opioid withdrawal

Morphine showed no clear difference in treatment failure To discharge compared with methadone (low certainty).

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
RR 1.59 [0.95, 2.67]
2 studies · 147 participants
Low

Morphine vs methadone

Seizures · newborn infants with opioid withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Opioid treatment for opioid withdrawal in newborn infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High MCT formula vs low MCT formula

Weight gain · promoting short‐term growth of preterm infants

2 findings from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 118 participants
Low
High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

High MCT formula vs low MCT formula

Length gain, cm/week (high MCT vs low MCT) · promoting short‐term growth of preterm infants

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 61 participants
Very low

High MCT formula vs low MCT formula

Growth: head circumference (cm/week) · promoting short‐term growth of preterm infants

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 61 participants
Low

High MCT formula vs low MCT formula

Skinfold thickness gain (mm/week) (high MCT vs low MCT) · promoting short‐term growth of preterm infants

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 32 participants
Very low

High MCT formula vs low MCT formula

Gastrointestinal intolerance · promoting short‐term growth of preterm infants

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 145 participants
Very low

High MCT formula vs low MCT formula

NEC · promoting short‐term growth of preterm infants

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 82 participants
Very low

High MCT formula vs low MCT formula

Neurodevelopmental outcomes · promoting short‐term growth of preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found