Findings

What do systematic reviews say?

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

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No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Bisphosphonates vs control

Femoral neck bone mineral density (FN-BMD) · adults with GIOP

1 finding from 1 review

Bisphosphonates for steroid‐induced osteoporosis 2016 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 1665 participants
Moderate

Bisphosphonates vs control

Serious adverse events · adults with GIOP

Bisphosphonates showed no clear difference in serious adverse events compared with control (low certainty).

1 finding from 1 review

Bisphosphonates for steroid‐induced osteoporosis 2016 · Cochrane Headline outcomes only
RR 0.91 [0.74, 1.12]
15 studies · 1703 participants
Low

Bisphosphonates vs control

Withdrawals due to adverse events · adults with GIOP

Bisphosphonates showed no clear difference in withdrawals due to adverse events compared with control (low certainty).

1 finding from 1 review

Bisphosphonates for steroid‐induced osteoporosis 2016 · Cochrane Headline outcomes only
RR 1.06 [0.77, 1.47]
15 studies · 1790 participants
Low

Bisphosphonates vs control

Quality of life · adults with GIOP

1 finding from 1 review

Bisphosphonates for steroid‐induced osteoporosis 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Pain on a 0 to 100 scale. Various pain scales. (lower score is better)

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1135 participants
Moderate

Intervention not reported

Disability on a 0 to 100 scale. Various disability scales (lower score is better)

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1116 participants
Moderate

Intervention not reported

Quality of life on a 0 to 100 scale. Various quality of life scales. (higher score is better)

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1027 participants
Moderate

Intervention not reported

Withdrawals

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1190 participants
Moderate

Intervention not reported

Radiographic evaluation

The review found no eligible studies for this question.

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Short term serious adverse effects from trials

The review found no eligible studies for this question.

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Long term adverse effects or toxicity from observational studies

The review found no eligible studies for this question.

1 finding from 1 review

Aquatic exercise for the treatment of knee and hip osteoarthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Fatigue continuous measures · patients with fatigue in rheumatoid arthritis

1 finding from 1 review

Biologic interventions for fatigue in rheumatoid arthritis 2016 · Cochrane Headline outcomes only
no estimate extracted
30 studies · 14628 participants
Moderate

Intervention not reported

Pain · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Global assessment of treatment success Satisfactory pace of recovery · people following primary uncemented THA

It is very uncertain whether the intervention changes global assessment of treatment success Satisfactory pace of recovery (very low certainty).

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
RR 0.83 [0.75, 0.93]
1 study · 303 participants
Very low

Intervention not reported

Hip dislocation Incidence of event · people following primary uncemented THA

It is very uncertain whether the intervention changes hip dislocation Incidence of event (very low certainty).

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
RR 2.98 [0.12, 72.59]
1 study · 303 participants
Very low

Intervention not reported

Reoperation rate1 · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Total adverse events Incidence of event · people following primary uncemented THA

It is very uncertain whether the intervention changes total adverse events Incidence of event (very low certainty).

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
RR 0 [0, 0]
1 study · 303 participants
Very low

Intervention not reported

Pain · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Function Objective Functional Capacity Index and Subjective Functional Capacity Index · people following primary uncemented THA

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Very low