Findings

What do systematic reviews say?

1,139 questions · 1,173 findings · 89 reviews · Neuromuscular

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No studies found 302 · 25.7%GRADE not reported 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%

Quinine vs a quinine‐vitamin E combination (Q‐Vel)

Major adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 510 participants
Moderate

Quinine vs a quinine‐vitamin E combination (Q‐Vel)

Minor adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 510 participants
Moderate

Quinine vs placebo

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 666 participants
Moderate

Quinine vs placebo

Major adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 1103 participants
Moderate

Quinine vs placebo

Minor adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 969 participants
Moderate

Quinine vs vitamin E

Number of cramps over 2 weeks · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 513 participants
Low

Quinine vs vitamin E

Cramp intensity (on 3‐point scale; 1 = mild; 2 = moderate; 3 = severe) · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 513 participants
Moderate

Quinine vs vitamin E

Major adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 513 participants
Moderate

Quinine vs vitamin E

Minor adverse events · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 483 participants
Moderate

Quinine vs a quinine‐vitamin E combination (Q‐Vel)

Number of cramps over 2 weeks · patients with muscle cramps

1 finding from 1 review

Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 486 participants
Low

Plasma exchange vs sham exchange

Change in disability Neuropathy Disability Score · people with IgG and IgA paraproteinaemic neuropathy

1 finding from 1 review

Treatment for IgG and IgA paraproteinaemic neuropathy 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Low

Plasma exchange vs sham exchange

Change in sensation using a validated scale (e.g. INCAT sensory sum score) ‐ not measured · people with IgG and IgA paraproteinaemic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for IgG and IgA paraproteinaemic neuropathy 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Plasma exchange vs sham exchange

Change in strength Neuropathy Disability Score (weakness) · people with IgG and IgA paraproteinaemic neuropathy

1 finding from 1 review

Treatment for IgG and IgA paraproteinaemic neuropathy 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Low

Plasma exchange vs sham exchange

Adverse events ‐ not reported · people with IgG and IgA paraproteinaemic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for IgG and IgA paraproteinaemic neuropathy 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVIg vs placebo

Activity limitations · people with postpolio syndrome

2 findings from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 185 participants
Moderate
Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Low

Amantadine vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Amantadine vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
GRADE not reported

Prednisone vs placebo

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prednisone vs placebo

Adverse events · people with postpolio syndrome

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
GRADE not reported

Muscle strengthening vs control

Activity limitations ‐ not measured · people with postpolio syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for postpolio syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found