Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,495 questions · 1,554 findings · 140 reviews · Heart

No studies found 272 · 17.5%GRADE not reported 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Exercise vs no exercise at longest available follow‐up

ICD, appropriate shock ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes ICD, appropriate shock ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

ICD, all shocks ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes ICD, all shocks ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

All‐cause mortality ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes all‐cause mortality ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Exercise vs no exercise at longest available follow‐up

Serious adverse events ( · adult patients with an implantable cardioverter defibrillator

It is very uncertain whether exercise changes serious adverse events ( compared with no exercise at longest available follow‐up (very low certainty).

1 finding from 1 review

Beta‐blockers vs placebo or no intervention

MACE · patients with suspected or diagnosed myocardial infarction

It is very uncertain whether beta‐blockers changes MACE (major adverse cardiovascular event) at maximum compared with placebo or no intervention (very low certainty).

2 findings from 1 review

Beta‐blockers vs placebo or no intervention

Angina · patients with suspected or diagnosed myocardial infarction

It is very uncertain whether beta‐blockers changes angina at maximum compared with placebo or no intervention (very low certainty).

2 findings from 1 review

Beta‐blockers vs placebo or no intervention

Cardiovascular mortality · patients with suspected or diagnosed myocardial infarction

Beta‐blockers probably leads to lower cardiovascular mortality at maximum compared with placebo or no intervention (moderate certainty).

2 findings from 1 review