Findings

What do systematic reviews say?

2,119 questions · 2,206 findings · 117 reviews · Common Mental Disorders

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No studies found 387 · 17.5%GRADE not reported 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Intervention not reported

Cost‐effectiveness of interventions · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Study withdrawal · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Change in hospital admission rates · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cost‐effectiveness of interventions · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Suicide (Observation period ‐ pre‐intervention: 89 years; postintervention 78.5 years) · adults or children of all ethnicities

The intervention may leads to lower suicide (Observation period ‐ pre‐intervention: 89 years;… (low certainty).

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
IRR 0.05
9 studies · 9 participants
Low

Intervention not reported

Attempted suicide · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Study withdrawal · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Change in hospital admission rates · adults or children of all ethnicities

The review found no eligible studies for this question.

1 finding from 1 review

Means restriction for the prevention of suicide by jumping 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants plus benzodiazepines vs antidepressants alone

Depression severity ‐ mean EPDS score (early phase, < 5 weeks) · patients with major depression

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 598 participants
Moderate

Antidepressants plus benzodiazepines vs antidepressants alone

Depression severity (acute phase, 5 ≤ 12 weeks) · patients with major depression

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 347 participants
Low

Antidepressants plus benzodiazepines vs antidepressants alone

Depression severity: continuous phase (> 12 weeks) · patients with major depression

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Antidepressants plus benzodiazepines vs antidepressants alone

Acceptability ‐ total dropouts · patients with major depression

Antidepressants plus benzodiazepines showed no clear difference in acceptability of treatment (dropout for any reason) compared with antidepressants alone (moderate certainty).

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
RR 0.76 [0.54, 1.07]
10 studies · 731 participants
Moderate

Antidepressants plus benzodiazepines vs antidepressants alone

Anxiety · patients with major depression

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 129 participants
Very low

Antidepressants plus benzodiazepines vs antidepressants alone

Adverse effects (dropouts) · patients with major depression

Antidepressants plus benzodiazepines probably leads to lower adverse effects (dropouts) compared with antidepressants alone (moderate certainty).

1 finding from 1 review

Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes only
RR 0.54 [0.32, 0.9]
10 studies · 731 participants
Moderate

Exercise therapy vs control

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 840 participants
Moderate

Exercise therapy vs control

Depression Measured at end of treatment; 12‐26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 504 participants
Very low

Exercise therapy vs control

Depression Measured after 52‐70 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 654 participants
Very low

Exercise therapy vs control

Sleep · men and women aged over 18 years with chronic fatigue syndrome

2 findings from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 323 participants
Low
Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 610 participants
Low

Exercise therapy vs psychological treatment

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

2 findings from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 298 participants
Low
Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 351 participants
Moderate

Exercise therapy vs psychological treatment

Participants with serious adverse reactions · men and women aged over 18 years with chronic fatigue syndrome

It is very uncertain whether exercise therapy changes participants with serious adverse reactions Measured after 52 weeks… compared with psychological treatment (very low certainty).

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
RR 0.67 [0.11, 3.96]
1 study · 321 participants
Very low