Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Intervention not reported

Lower limb compression vs control · women having spinal anaesthesia for caesarean section

It is very uncertain whether the intervention changes lower limb compression vs control (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo or no treatment

Neonatal death (baby born alive at any gestation and dies within 28 days) · infants born of women at risk of preterm birth

Neonatal and child outcomes: corticosteroids leads to lower neonatal death (infants born with signs of life who die within the… compared with placebo or no treatment (high certainty).

1 finding from 1 review

Corticosteroids vs placebo or no treatment

Respiratory distress syndrome · infants born of women at risk of preterm birth

Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).

1 finding from 1 review

Corticosteroids vs placebo or no treatment

Intraventricular haemorrhage · infants born of women at risk of preterm birth

Neonatal and child outcomes: corticosteroids probably leads to lower intraventricular haemorrhage (IVH)№ of participants: 8475(12 RCTs) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo or no treatment

Developmental delay in childhood№ of participants: 600 (3 RCTs). Age at · infants born of women at risk of preterm birth

Neonatal and child outcomes: corticosteroids probably leads to lower developmental delay in childhood№ of participants: 600 (3 RCTs). Age… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review