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Evidence found and GRADE certainty

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

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No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Incidence of type 2 diabetes mellitus Measured as 2 consecutive fasting blood glucose values ≥ 6.1 mmol/L (NANSY 2011b) or no definition provided (Eriksson 2006) · people at risk for the development of type 2 diabetes mellitus

It is very uncertain whether the intervention changes incidence of type 2 diabetes mellitus Measured as 2 consecutive… (very low certainty).

1 finding from 1 review

Intervention not reported

Incidence of type 2 diabetes mellitus Defined as: fasting plasma glucose ≥ 7.0 mmol/L (126 mg/dL) or a 2‐hour blood glucose after a glucose‐load test ≥ 11.1 mmol/L (200 mg/dL) or by an adjudication committeeb · people at risk for the development of type 2 diabetes mellitus
1 finding from 1 review

Intervention not reported

Adverse events a. Serious adverse events b. Discontinuation of trial because of adverse events · obese children and adolescents

The intervention showed no clear difference in adverse events a. Serious adverse events b. Discontinuation of trial… (low certainty).

1 finding from 1 review