Severity of depression dichotomous measures ‐ "very much" or "much" improved on the Clinical Global Impression Scale · patients with depression during opioid agonist treatment for opioid dependence
Antidepressants may leads to higher severity of depression dichotomous measures ‐ "very much" or "much"… compared with placebo according to any definition (low certainty).
1 finding from 1 review
Severity of depression continuous measures ‐ HDRS total score at the end of the treatment · patients with depression during opioid agonist treatment for opioid dependence
1 finding from 1 review
Adverse events ‐ Withdrawn for medical reasons · patients with depression during opioid agonist treatment for opioid dependence
Antidepressants probably leads to higher adverse events ‐ Withdrawn for medical reasons compared with placebo according to any definition (moderate certainty).
1 finding from 1 review
Dropout · patients with depression during opioid agonist treatment for opioid dependence
Antidepressants showed no clear difference in dropout compared with placebo (moderate certainty).
1 finding from 1 review
Severity of depression dichotomous measures ‐ "very much" or "much" improved on the Clinical Global Impression Scale · patients with depression during opioid agonist treatment for opioid dependence
Antidepressants may leads to higher severity of depression dichotomous measures ‐ "very much" or "much"… compared with placebo (low certainty).
1 finding from 1 review
> 50% reduction in depressive symptoms · patients with depression during opioid agonist treatment for opioid dependence
Antidepressants showed no clear difference in severity of depression dichotomous measures ‐ >50% reduction in… compared with placebo (low certainty).
1 finding from 1 review
Intervention not reported
Retention in treatment ‐ Old studies (pre 2000) objective · patients with opioid dependence
The intervention leads to higher retention in treatment ‐ Old studies (pre 2000) objective (high certainty).
1 finding from 1 review
Intervention not reported
Retention in treatment ‐ New studies · patients with opioid dependence
The intervention leads to higher retention in treatment ‐ New studies (high certainty).
1 finding from 1 review
Intervention not reported
Morphine positive urine or hair analysis objective · patients with opioid dependence
The intervention leads to lower morphine positive urine or hair analysis objective (high certainty).
1 finding from 1 review
Intervention not reported
Criminal activity objective · patients with opioid dependence
The intervention showed no clear difference in criminal activity objective (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality objective · patients with opioid dependence
The intervention showed no clear difference in mortality objective (moderate certainty).
1 finding from 1 review