Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

762 questions · 830 findings · 43 reviews · Orthodontics

No studies found 186 · 22.4%GRADE not reported 410 · 49.4%Very low 122 · 14.7%Low 79 · 9.5%Moderate 30 · 3.6%High 3 · 0.4%

CBT vs No special instructions (control)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults undergoing orthodontic treatment

Cognitive behavioural therapy (CBT) led to lower patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no special instructions (control); GRADE not reported.

3 findings from 1 review

Low‐level laser therapy vs Placebo (or no irradiation)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Low‐level laser therapy (LLLT) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with placebo (or no irradiation); GRADE not reported.

5 findings from 1 review
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Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents/teenagers undergoing orthodontic treatment

Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.

5 findings from 1 review
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Chemically cured zinc phosphate cement vs Glass ionomer cement (GIC)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    No meta-analysis (band failure not reported on a per-patient basis). Durning 1989 (69 participants): at ~12 months failure rate 34.78% (zinc phosphate) vs 26% (glass ionomer), P > 0.05; mean survival time 470.9 vs…
    4 studies
    GRADE not reported

Post‐treatment communication (text messaging) vs No communication (no text message)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no vibration or placebo vibration; GRADE not reported.

5 findings from 1 review
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Zinc polycarboxylate cement vs Any other orthodontic band adhesive

Outcome not reported · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

The review found no eligible studies for this question.

1 finding from 1 review

Chemically cured glass ionomer cement vs Chemically cured glass phosphonate

Taste preference (patient preference) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    Clark 2003: no statistically significant difference in taste between the two cements (glass ionomer vs glass phosphonate); authors caution the finding because both cements were used at the same sitting, so the taste of…
    1 study
    GRADE not reported

Brain wave music (BWM) vs No special instructions (control)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults undergoing orthodontic treatment

Brain wave music (BWM) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no special instructions (control); GRADE not reported.

3 findings from 1 review

Chemically cured zinc phosphate cement vs Glass ionomer cement (GIC)

Decalcification · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    No statistical analysis. Kvam 1983 (28 participants): 4 teeth affected by small decalcification spots (reversed by polishing and fluoride), all with the zinc phosphate cement. Galarraga 2003 (40 participants): 8…
    2 studies · 68 participants
    GRADE not reported

Psychological intervention: structured telephone call (verbal follow‐up and reassurance) vs placebo or no intervention

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Dose/intensity and frequency of pain relief needed (analgesic/rescue medication use) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) led to lower dose/intensity and frequency of pain relief needed (analgesic/rescue… compared with no vibration or placebo vibration; GRADE not reported.

1 finding from 1 review

Chemically cured glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)

Decalcification · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    Gillgrass 2001 (98 participants): comparison of change in mean enamel white spot lesion scores during treatment showed no statistically significant difference between chemically cured glass ionomer and light-cured…
    1 study · 98 participants
    GRADE not reported