Findings

What do systematic reviews say?

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

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No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Diabetes‐related morbidity

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Patient satisfaction

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events: a. hypoglycaemia (% of participants)

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 503 participants
Low

Intervention not reported

HbA1c, change from baseline (%)

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 265 participants
Low

Intervention not reported

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Patient satisfaction

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events: a. mild hypoglycaemia (episodes per participant)

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 239 participants
Low

Intervention not reported

HbA1c, change from baseline (%)

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 316 participants
Low

Intervention not reported

All‐cause mortality

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Diabetes‐related mortality

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Supportive interventions for enhancing dietary intake vs comparators

All‐cause mortality · malnourished or nutritionally at‐risk adults

Supportive interventions for enhancing dietary intake probably leads to lower all‐cause mortality compared with comparators (moderate certainty).

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
RR 0.78 [0.66, 0.92]
12 studies · 6683 participants
Moderate

Supportive interventions for enhancing dietary intake vs comparators

Complications and morbidity (6 ‐ 8 weeks) · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 4015 participants
Very low

Supportive interventions for enhancing dietary intake vs comparators

Health‐related quality of life and patient satisfaction · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 4451 participants
Low

Supportive interventions for enhancing dietary intake vs comparators

Hospitalisation and institutionalisation (days) · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 667 participants
Very low

Supportive interventions for enhancing dietary intake vs comparators

Adverse events · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 4108 participants
Very low

Supportive interventions for enhancing dietary intake vs comparators

Change in weight (kg) · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 2024 participants
Moderate

Supportive interventions for enhancing dietary intake vs comparators

Costs · malnourished or nutritionally at‐risk adults

1 finding from 1 review

Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1152 participants
Very low

Intervention not reported

Health‐related quality of life [measured by the validated questionnaire SF‐36]

1 finding from 1 review

Radioiodine therapy versus antithyroid medications for Graves' disease 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 425 participants
GRADE not reported

Intervention not reported

Development and worsening of Graves' ophthalmopathy [examination by ophthalmologists]

The intervention may leads to higher development and worsening of Graves' ophthalmopathy [examination by… (low certainty).

1 finding from 1 review

Radioiodine therapy versus antithyroid medications for Graves' disease 2016 · Cochrane Headline outcomes only
RR 1.94 [1.4, 2.7]
2 studies · 417 participants
Low