Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Plasma expanders vs no plasma expanders

Other liver‐related complications · cirrhotic participants with large ascites treated by paracentesis

It is very uncertain whether plasma expanders changes other liver‐related complications compared with no plasma expanders (very low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality · people with liver metastases

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

Intervention not reported

Cancer mortality · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All adverse events and complications · people with liver metastases

The intervention led to higher all adverse events and complications; GRADE not reported.

1 finding from 1 review

Intervention not reported

Health‐related quality of life · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Recurrence of liver metastases Number of participants developing recurrences of liver metastases · people with liver metastases

The intervention showed no clear difference in recurrence of liver metastases Number of participants developing… (low certainty).

1 finding from 1 review

Intervention not reported

Time to progression of liver metastases · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Tumour response measures · people with liver metastases
1 finding from 1 review