Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,187 questions · 1,248 findings · 108 reviews · Stroke

No studies found 275 · 22%GRADE not reported 56 · 4.5%Very low 269 · 21.6%Low 349 · 28%Moderate 216 · 17.3%High 83 · 6.7%

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke between randomisation and 30 days after treatment compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke between randomisation and 30 days after… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or major or disabling stroke between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or major or disabling stroke between randomisation and 30 days… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke between randomisation and 30 days after treatment compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke between randomisation and 30 days after… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or major or disabling stroke between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or major or disabling stroke between randomisation and 30 days… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Intervention not reported

Any stroke or operative death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in any stroke or operative death (five‐year cumulative) (moderate certainty).

1 finding from 1 review

Intervention not reported

Ipsilateral ischaemic stroke, and any operative stroke or death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in ipsilateral ischaemic stroke, and any operative stroke or death… (moderate certainty).

1 finding from 1 review

Intervention not reported

Disabling or fatal ipsilateral ischaemic or operative stroke and death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in disabling or fatal ipsilateral ischaemic or operative stroke and… (moderate certainty).

1 finding from 1 review