Findings

What do systematic reviews say?

592 questions · 793 findings · 32 reviews · Periodontology

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No studies found 148 · 18.7%GRADE not reported 429 · 54.1%Very low 137 · 17.3%Low 53 · 6.7%Moderate 14 · 1.8%High 12 · 1.5%

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Tooth loss · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Systemic oral acyclovir vs placebo or no treatment

Difficulty in drinking (number with drinking difficulties) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

Systemic oral acyclovir led to lower number of individuals with drinking difficulties (8 days after… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
8 days after administration
RR 0.11 [0.01, 0.83]
1 study · 72 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Tooth loss · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.40 [0.05, 0.75]
1 study · 50 participants
GRADE not reported

Systemic oral acyclovir vs placebo or no treatment

Number of individuals admitted to hospital after administration · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

Systemic oral acyclovir showed no clear difference in number of individuals admitted to hospital after administration compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
After administration
RR 0.14 [0.01, 2.67]
1 study · 72 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Systemic oral acyclovir vs placebo or no treatment

Duration of fever · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
Amir 1997b: fever disappeared significantly earlier with acyclovir (median 1 day) than placebo (median 3 days); difference in median (95% CI): From 72: 1 (0.0 to 2.0); From 61: 2 (0.8 to 3.2); reported as median, not…
2 studies
GRADE not reported

One type of occlusal intervention as an adjunct to periodontal therapy vs A different type of occlusal intervention as an adjunct to periodontal therapy (head-to-head)

Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Systemic oral acyclovir vs placebo or no treatment

Patient or parental satisfaction (tolerance and acceptability of drug) · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
Amir 1997b: no data available. Ducoulombier 1988: tolerance and acceptability of the drug was described as satisfactory, but it was unclear how this was assessed by the trialists.
1 study
GRADE not reported

Systemic oral acyclovir vs placebo or no treatment

Adverse effects · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
Amir 1997b: two children in each group (2 vs 2) had mild gastrointestinal symptoms that resolved spontaneously after 24 to 48 hours without a change in study treatment. Ducoulombier 1988: no significant adverse effects…
2 studies
GRADE not reported

Occlusal intervention as an adjunct to periodontal therapy vs Sham (placebo) occlusal intervention as an adjunct to periodontal therapy

Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Systemic oral acyclovir vs placebo or no treatment

QoL · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

The review found no eligible studies for this question.

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
No data were available in either included study (Amir 1997b; Ducoulombier 1988).
Studies not reported
No studies found

Systemic oral acyclovir vs placebo or no treatment

Mean time to resolution of pain · Children and young adults under 25 years with primary herpetic gingivostomatitis (with or without herpes labialis)

1 finding from 1 review

Acyclovir for treating primary herpetic gingivostomatitis 2008 · Cochrane All outcomes
Amir 1997b: no data available. Ducoulombier 1988: time to resolution of pain, acyclovir (1 day=1, 2 days=1, 3 days=3, 4 days=3, 5 days=1, persistent=0) vs placebo (1 day=0, 2 days=0, 3 days=1, 4 days=2, 5 days=4,…
1 study · 18 participants
GRADE not reported

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Change in probing pocket depth (PPD) · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.01 [-0.20, 0.22]
1 study · 50 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.38 [0.04, 0.72]
1 study · 50 participants
GRADE not reported

Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs usual care or no treatment

Observed flossing skill · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis)

1 finding from 1 review

Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases 2007 · Cochrane All outcomes
4 months
Little 1997 observed and rated participants on flossing skill; Analysis of Covariance found a significant difference favouring the intervention group.
1 study · 107 participants
GRADE not reported

Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs usual care or no treatment

Plaque · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis)

1 finding from 1 review

Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases 2007 · Cochrane All outcomes
The impact of psychological interventions on clinical markers was assessed in three studies (Little 1997; Stewart 1991; Weinstein 1996). All three found that psychological interventions resulted in improved plaque…
3 studies
GRADE not reported

Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs usual care or no treatment

Self-efficacy beliefs (flossing) · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis)

1 finding from 1 review

Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases 2007 · Cochrane All outcomes
Stewart 1996: the psychological intervention group demonstrated significantly higher change in self efficacy scores for flossing at post-intervention compared to the other two groups (control and educational). Flossing…
1 study · 117 participants
GRADE not reported

Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs attention control

Plaque · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis)

1 finding from 1 review

Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases 2007 · Cochrane All outcomes
Weinstein 1996 reported that the psychological intervention led to improvements in plaque score greater than that noted in the attention control group; however the sample size in each arm was very small (n=5) and the…
2 studies
GRADE not reported

Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs usual care or no treatment

Probing pocket depth (PPD/PD) · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis)

1 finding from 1 review

Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases 2007 · Cochrane All outcomes
4 months
Little 1997: no change in pocket depth; there were no differences between the intervention and control groups in overall change in pocket depth. (Some analyses suggested greater change in the intervention group when…
1 study · 107 participants
GRADE not reported