Findings

What do systematic reviews say?

1,444 questions · 1,518 findings · 135 reviews · Infectious Diseases

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No studies found 135 · 8.9%GRADE not reported 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Intervention not reported

Failure of rehydration · acute diarrhoea in children

The intervention showed no clear difference in failure of rehydration (low certainty).

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
RR 0.41 [0.13, 1.23]
2 studies · 192 participants
Low

Intervention not reported

Duration of diarrhoea · acute diarrhoea in children

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 867 participants
Very low

Intervention not reported

Number of stools: measured in the first 24 hours after introduction of racecadotril · acute diarrhoea in children

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 258 participants
Very low

Intervention not reported

Stool output: measured in the first 48 hours after introduction of racecadotril · acute diarrhoea in children

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 301 participants
Low

Intervention not reported

Length of hospital stay for inpatients · acute diarrhoea in children

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 224 participants
Low

Intervention not reported

Adverse events: number of all types of adverse events · acute diarrhoea in children

The intervention showed no clear difference in adverse events: number of all types of adverse events (low certainty).

1 finding from 1 review

Racecadotril for acute diarrhoea in children 2019 · Cochrane Headline outcomes only
RR 0.9 [0.66, 1.22]
5 studies · 688 participants
Low

Intervention not reported

Death · children with severe malaria

The intervention showed no clear difference in death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.97 [0.77, 1.21]
13 studies · 1659 participants
Moderate

Intervention not reported

Fever clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 716 participants
Low

Intervention not reported

Death · adults with severe malaria

The intervention probably leads to higher death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 1.8 [1.09, 2.97]
2 studies · 494 participants
Moderate

Intervention not reported

Coma resolution time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Neurological sequelae at discharge · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Parasite clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Fever clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Coma resolution time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 358 participants
Low

Intervention not reported

Neurological sequelae at discharge · children with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.84 [0.66, 1.07]
7 studies · 968 participants
Low

Intervention not reported

Parasite clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 420 participants
Moderate

Intervention not reported

Fever clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 457 participants
Low

Intervention not reported

Death · adults with severe malaria

The intervention probably leads to lower death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.59 [0.42, 0.83]
4 studies · 716 participants
Moderate

Intervention not reported

Coma resolution time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 657 participants
Low

Intervention not reported

Neurological sequelae at discharge · adults with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 2.92 [0.31, 27.86]
1 study · 560 participants
Low