Findings

What do systematic reviews say?

1,562 questions · 1,645 findings · 107 reviews · Wounds

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No studies found 651 · 39.6%GRADE not reported 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Aqueous oxygen peroxide vs placebo (saline solution or sterile water)

Change in ulcer size · people with venous leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Very low

Aqueous oxygen peroxide vs placebo (saline solution or sterile water)

Procedural pain · people with venous leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Very low

Aqueous oxygen peroxide vs placebo (saline solution or sterile water)

Costs · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous oxygen peroxide vs placebo (saline solution or sterile water)

Health related quality of life · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Aqueous oxygen peroxide vs placebo (saline solution or sterile water)

Adverse events · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Ulcer healing · participants with chronic leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Number of wounds healed · participants with chronic leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Change in ulcer size · participants with chronic leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Propyl betaine and polihexanide vs Normal saline

Procedural pain · participants with chronic leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Propyl betaine and polihexanide vs Normal saline

Costs · participants with chronic leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Polyhexamethylene biguanide (PHMB) vs Normal saline

Number of wounds healed · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Health related quality of life · participants with chronic leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Propyl betaine and polihexanide vs Normal saline

Adverse events after 4 weeks of · participants with chronic leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

OHP vs Ringer's solution

Time to complete healing · participants with treating venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

OHP vs Ringer's solution

Number of wounds healed · participants with treating venous leg ulcers

It is very uncertain whether OHP changes number of wounds healed after 12 weeks of compared with ringer's solution (very low certainty).

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
RR 0.96 [0.53, 1.72]
1 study · 99 participants
Very low

OHP vs Ringer's solution

Change in ulcer size · participants with treating venous leg ulcers

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Very low

OHP vs Ringer's solution

Procedural pain · participants with treating venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

OHP vs Ringer's solution

Costs · participants with treating venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

OHP vs Ringer's solution

Health related quality of life · participants with treating venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

OHP vs Ringer's solution

Adverse events after week 12 of · participants with treating venous leg ulcers

It is very uncertain whether OHP changes adverse events after week 12 of compared with ringer's solution (very low certainty).

1 finding from 1 review

Wound cleansing for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
RR 0.58 [0.29, 1.14]
1 study · 126 participants
Very low