Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,293 questions · 2,395 findings · 172 reviews · Gut

No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

Antibiotics plus probiotics vs placebo or no intervention

Failure to induce clinical remission at end of study · people with active UC

It is very uncertain whether antibiotics plus probiotics changes failure to induce clinical remission at end of study compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Certolizumab pegol vs placebo

Failure to maintain clinical remission at end of study · people with Crohn's disease who responded to CZP remission‐induction treatment

Certolizumab pegol probably leads to lower failure to maintain clinical remission at week 26(1 RCT, 428… compared with placebo (moderate certainty).

1 finding from 1 review

Certolizumab pegol vs placebo

Any severe adverse event during maintenance treatment · people with Crohn's disease who responded to CZP remission‐induction treatment

Certolizumab pegol showed no clear difference in serious adverse events during remission maintenance treatment(1 RCT,… compared with placebo (low certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Technical success in insertion

Electromagnetic‐guided showed no clear difference in technical success in insertion compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Aspiration pneumonitis

Electromagnetic‐guided showed no clear difference in aspiration pneumonitis compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (low certainty).

1 finding from 1 review

Electromagnetic‐guided vs endoscopic‐guided postpyloric placement of nasoenteral feeding tubes

Adverse events

Electromagnetic‐guided showed no clear difference in adverse events compared with endoscopic‐guided postpyloric placement of nasoenteral feeding tubes (moderate certainty).

1 finding from 1 review