Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

475 questions · 487 findings · 49 reviews · Breast Cancer

No studies found 44 · 9%GRADE not reported 14 · 2.9%Very low 108 · 22.2%Low 128 · 26.3%Moderate 107 · 22%High 86 · 17.7%

Intervention not reported

Brain metastasis as first site of relapse · HER2‐positive early breast cancer patients

The intervention may leads to higher brain metastasis as first site of relapse (low certainty).

1 finding from 1 review

Intervention not reported

Chemotherapy Rates of patients who received the planned chemotherapy doses at scheduled times and doses · breast cancer patients undergoing chemotherapy

The intervention showed no clear difference in chemotherapy Rates of patients who received the planned chemotherapy… (low certainty).

1 finding from 1 review