Findings

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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Injectional nicardipine vs Normal saline

Treatment‐related adverse effects · men with chronic Peyronie's disease (plaques without calcification)

It is very uncertain whether injectional nicardipine changes treatment‐related adverse effects compared with saline (very low certainty).

1 finding from 1 review

Potassium paraaminobenzoate vs placebo

Patient‐reported ability to have intercourse · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

Potassium paraaminobenzoate showed no clear difference in patient‐reported ability to have intercourse compared with placebo (low certainty).

1 finding from 1 review