Findings

What do systematic reviews say?

4,811 questions · 70,850 findings · 5,139 reviews

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No studies found 15,174 · 21.4%GRADE not reported 6,479 · 9.1%Very low 17,330 · 24.5%Low 17,814 · 25.1%Moderate 11,056 · 15.6%High 2,997 · 4.2%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Intervention not reported

Mobility · people with β‐thalassaemia and osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · people with β‐thalassaemia and osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse effects of treatment · people with β‐thalassaemia and osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

BMD Z score (total hip/femoral neck) · children and adults with β‐thalassaemia major and low bone mass

Summary of findings – zinc probably leads to higher BMD Z score (total hip/femoral neck) compared with placebo (moderate certainty).

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
MD 0.15 [0.11, 0.19]
1 study · 37 participants
Moderate

Zinc vs placebo

BMD Z score (lumbar spine) · children and adults with β‐thalassaemia major and low bone mass

Summary of findings – zinc probably leads to higher BMD Z score (lumbar spine) compared with placebo (moderate certainty).

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
MD 0.15 [0.1, 0.2]
1 study · 37 participants
Moderate

Zinc vs placebo

BMD Z score (wrist) · children and adults with β‐thalassaemia major and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

Incidence of fractures · children and adults with β‐thalassaemia major and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

Mobility · children and adults with β‐thalassaemia major and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bisphosphonates vs placebo or no treatment

BMD Z score (lumbar spine) · adults with β‐thalassaemia and osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

Quality of life · children and adults with β‐thalassaemia major and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

Adverse effects of treatment · children and adults with β‐thalassaemia major and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings – denosumab vs placebo

BMD Z score (total hip/femoral neck) · adults with β‐thalassaemia and low bone mass

Summary of findings – denosumab showed no clear difference in BMD Z score (total hip/femoral neck) compared with placebo (low certainty).

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
MD 0.05
1 study · 63 participants
Low

Summary of findings – denosumab vs placebo

BMD Z score (lumbar spine) · adults with β‐thalassaemia and low bone mass

Summary of findings – denosumab showed no clear difference in BMD Z score (lumbar spine) compared with placebo (low certainty).

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Low

Summary of findings – denosumab vs placebo

BMD Z score (wrist) · adults with β‐thalassaemia and low bone mass

Summary of findings – denosumab showed no clear difference in BMD Z score (wrist) compared with placebo (low certainty).

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Low

Summary of findings – denosumab vs placebo

Incidence of fractures · adults with β‐thalassaemia and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings – denosumab vs placebo

Mobility · adults with β‐thalassaemia and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings – denosumab vs placebo

Quality of life · adults with β‐thalassaemia and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings – denosumab vs placebo

Adverse effects of treatment · adults with β‐thalassaemia and low bone mass

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings – strontium ranelate vs placebo

BMD Z score (total hip/femoral neck) · women with low bone mass and β‐thalassaemia

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bisphosphonates vs placebo or no treatment

BMD Z score (wrist) · adults with β‐thalassaemia and osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment for osteoporosis in people with beta‐thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found