Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Caesarean delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in caesarean delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Instrumental delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in instrumental delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Intervention not reported

Live birth rate · couples trying to conceive

The intervention probably leads to higher live birth rate (moderate certainty).

1 finding from 1 review

Intervention not reported

Pregnancy rate (clinical or positive urine pregnancy test) · couples trying to conceive

It is very uncertain whether the intervention changes pregnancy rate (clinical or positive urine pregnancy test) (very low certainty).

1 finding from 1 review

Intervention not reported

Time to pregnancy · couples trying to conceive

The intervention showed no clear difference in time to pregnancy (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life – not reported · couples trying to conceive

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events · couples trying to conceive

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy rate · couples trying to conceive

The intervention showed no clear difference in clinical pregnancy rate (low certainty).

1 finding from 1 review

Intervention not reported

Pregnancy rate(clinical pregnancy or urine pregnancy test) · couples trying to conceive

The intervention probably leads to higher pregnancy rate(clinical pregnancy or urine pregnancy test) (moderate certainty).

1 finding from 1 review

Intervention not reported

Time to pregnancy · couples trying to conceive

It is very uncertain whether the intervention changes time to pregnancy (very low certainty).

1 finding from 1 review

Intervention not reported

Live birth rate · couples trying to conceive

The intervention showed no clear difference in live birth rate (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events · couples trying to conceive

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy rate · couples trying to conceive

It is very uncertain whether the intervention changes clinical pregnancy rate (very low certainty).

1 finding from 1 review

Intervention not reported

Gestational diabetes mellitus · pregnant women (women with pre‐existing type 1 or type 2 diabetes are NOT included)

It is very uncertain whether the intervention changes gestational diabetes mellitus (very low certainty).

1 finding from 1 review