Findings

What do systematic reviews say?

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

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No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Sublingual glucose vs oral (swallowed) glucose

Resolution of symptoms · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Resolution of hypoglycaemia · healthy adults

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Time to resolution of hypoglycaemia · healthy adults

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Adverse events · healthy adults

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Ease of administration/treatment delay · healthy adults

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dextrose gel vs oral (swallowed) glucose

Resolution of symptoms · adult patients with insulin‐dependent diabetes

It is very uncertain whether oral + buccal glucose (dextrose gel) changes resolution of symptoms within 20 minutes compared with oral (swallowed) glucose (very low certainty).

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
RR 0.36 [0.12, 1.14]
1 study · 18 participants
Very low

Dextrose gel vs oral (swallowed) glucose

Time to symptom resolution · adult patients with insulin‐dependent diabetes

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dextrose gel vs oral (swallowed) glucose

Blood/plasma glucose concentrations at 20 minutes · adult patients with insulin‐dependent diabetes

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Dextrose gel vs oral (swallowed) glucose

Resolution of hypoglycaemia · adult patients with insulin‐dependent diabetes

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dextrose gel vs oral (swallowed) glucose

Time to resolution of hypoglycaemia · adult patients with insulin‐dependent diabetes

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dextrose gel vs oral (swallowed) glucose

Adverse events · adult patients with insulin‐dependent diabetes

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sublingual glucose vs oral (swallowed) glucose

Blood/plasma glucose concentrations at 20 minutes · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Dextrose gel vs oral (swallowed) glucose

Ease of administration/treatment delay · adult patients with insulin‐dependent diabetes

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sublingual glucose vs oral (swallowed) glucose

Resolution of hypoglycaemia · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

It is very uncertain whether sublingual glucose changes resolution of hypoglycaemia Definition: (a) within 20 minutes (b)… compared with oral (swallowed) glucose (very low certainty).

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
RR 1.26 [0.91, 1.74]
1 study · 42 participants
Very low

Sublingual glucose vs oral (swallowed) glucose

Time to resolution of hypoglycaemia · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Sublingual glucose vs oral (swallowed) glucose

Adverse events · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Sublingual glucose vs oral (swallowed) glucose

Delay in treatment · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Resolution of symptoms · healthy adults

The review found no eligible studies for this question.

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Buccal glucose vs oral (swallowed) glucose

Blood/plasma glucose concentrations at 20 minutes · healthy adults

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Buccal glucose vs oral (swallowed) glucose

Increased blood glucose at 20 minutes · healthy adults

It is very uncertain whether buccal glucose changes increased blood glucose at 20 minutes compared with oral (swallowed) glucose (very low certainty).

1 finding from 1 review

First aid glucose administration routes for symptomatic hypoglycaemia 2019 · Cochrane Headline outcomes only
RR 0.07 [0, 0.98]
1 study · 7 participants
Very low