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What do systematic reviews say?

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Evidence found and GRADE certainty

996 questions · 1,049 findings · 79 reviews · Dementia and Cognitive Improvement

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No studies found 240 · 22.9%GRADE not reported 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Souvenaid vs placebo

Incidence of dementia · People with MCI/prodromal AD

Souvenaid showed no clear difference in incidence of dementia compared with placebo (moderate certainty).

1 finding from 1 review

Souvenaid vs placebo

Any adverse events · People with mild Alzheimer's disease

Souvenaid showed no clear difference in any adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Souvenaid vs placebo

Memory (specific cognitive function) · Apathy in people with mild‐to‐moderate Alzheimer's disease
1 finding from 1 review

Souvenaid vs placebo

Executive function (specific cognitive function) · Apathy in people with mild‐to‐moderate Alzheimer's disease
1 finding from 1 review

Souvenaid vs placebo

Combined cognitive‐functional outcome · Apathy in people with mild‐to‐moderate Alzheimer's disease
1 finding from 1 review

Souvenaid vs placebo

Any adverse events · Apathy in people with mild‐to‐moderate Alzheimer's disease

Souvenaid showed no clear difference in any adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Souvenaid vs placebo

Any adverse event · People with MCI/prodromal AD

Souvenaid showed no clear difference in any adverse event compared with placebo (moderate certainty).

1 finding from 1 review