Findings

What do systematic reviews say?

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

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No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Steroid implant vs sham

Mean difference in BCVA (logMAR) · people with chronic non‐infectious uveitis

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 153 participants
Low

Steroid implant vs sham

Improvement in quality of life: the difference in quality of life scores for participants surveyed before and after treatment · people with chronic non‐infectious uveitis

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Moderate

Steroid implant vs sham

Proportion of eyes with cataract formation or progression, or surgery · people with chronic non‐infectious uveitis

Steroid implant may leads to higher proportion of participants with cataract formation/progression, or… compared with sham procedure (low certainty).

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
RR 2.69 [1.17, 6.18]
1 study · 90 participants
Low

Steroid implant vs sham

Proportion of participants with elevated IOP or receiving intervention · people with chronic non‐infectious uveitis

Steroid implant probably leads to higher proportion of participants with elevated IOP or receiving intervention compared with sham procedure (moderate certainty).

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
RR 2.81 [1.42, 5.56]
2 studies · 282 participants
Moderate

Steroid implant vs sham

Proportion of participants with endophthalmitis · people with chronic non‐infectious uveitis

Steroid implant showed no clear difference in proportion of participants with endophthalmitis compared with sham procedure (moderate certainty).

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
RR 0.47 [0.1, 2.3]
2 studies · 280 participants
Moderate

Steroid implant vs sham

Proportion of participants with retinal tear or detachment · people with chronic non‐infectious uveitis

Steroid implant showed no clear difference in proportion of participants with retinal tear or detachment compared with sham procedure (moderate certainty).

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
RR 1.11 [0.21, 5.75]
2 studies · 280 participants
Moderate

Steroid implant vs standard‐of‐care therapy

Proportion of eyes with recurrence of uveitis · people with chronic non‐infectious uveitis

Steroid implant may leads to lower proportion of eyes with recurrence of uveitis compared with standard‐of‐care therapy (low certainty).

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
RR 0.46 [0.35, 0.6]
Studies not reported
Low

Steroid implant vs standard‐of‐care therapy

Mean difference in BCVA (logMAR) · people with chronic non‐infectious uveitis

1 finding from 1 review

Corticosteroid implants for chronic non‐infectious uveitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Device‐modified trabeculectomy vs trabeculectomy

Mean intraocular pressure · People with glaucoma

Device‐modified trabeculectomy showed no clear difference in postoperative mean IOP at 1 year compared with standard trabeculectomy (low certainty).

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Device‐modified trabeculectomy vs trabeculectomy

Postoperative mean change in IOP from baseline to 1 year · People with glaucoma

It is very uncertain whether device‐modified trabeculectomy changes postoperative mean change in IOP from baseline to 1 year compared with standard trabeculectomy (very low certainty).

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
MD 2
Studies not reported
Very low

Device‐modified trabeculectomy vs trabeculectomy

Postoperative mean logMAR BCVA at 1 year · People with glaucoma

Device‐modified trabeculectomy showed no clear difference in postoperative mean logMAR BCVA at 1 year compared with standard trabeculectomy (low certainty).

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Device‐modified trabeculectomy vs trabeculectomy

Mean change in visual field score from baseline at 1‐year · People with glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Device‐modified trabeculectomy vs trabeculectomy

Quality of life at 1 year · People with glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Device‐modified trabeculectomy vs trabeculectomy

Proportion of participants who were drop‐free · People with glaucoma

It is very uncertain whether device‐modified trabeculectomy changes proportion of participants who were drop‐free at 1 year compared with standard trabeculectomy (very low certainty).

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
RR 2.04 [0.42, 9.82]
Studies not reported
Very low

Device‐modified trabeculectomy vs trabeculectomy

Proportion of participants with endophthalmitis · People with glaucoma

It is very uncertain whether device‐modified trabeculectomy changes proportion of participants with endophthalmitis compared with standard trabeculectomy (very low certainty).

1 finding from 1 review

Device‐modified trabeculectomy for glaucoma 2023 · Cochrane Headline outcomes only
RR 0.34 [0.01, 8.29]
Studies not reported
Very low

Exercise vs no treatment

Intensity of disease signs and symptoms1 · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes intensity of disease signs and symptoms: VCSS Scale: 0 to 30 (lower… compared with no treatment (very low certainty).

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 49 participants
Very low

Exercise vs no treatment

Ejection fraction · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes ejection fraction compared with no treatment (very low certainty).

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
MD 4.88
1 study · 28 participants
Very low

Exercise vs no treatment

Venous refilling time · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes venous refilling time compared with no treatment (very low certainty).

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
MD 10.7
3 studies · 72 participants
Very low

Exercise vs no treatment

Incidence of venous leg ulcer · people with non‐ulcerated chronic venous insufficiency

The review found no eligible studies for this question.

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs no treatment

QoL · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes quality of life VEINES‐QOL/SF‐36/CIVIQ‐20 (lower is better) compared with no treatment (very low certainty).

1 finding from 1 review

Physical exercise for the treatment of non‐ulcerated chronic venous insufficiency 2023 · Cochrane Headline outcomes only
MD 4.6
2 studies · 61 participants
Very low