Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Multiple pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in multiple pregnancy rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).

1 finding from 1 review

Intervention not reported

Live birth or ongoing pregnancy: early (EFP) vs late (LFP) follicular phase · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: early (EFP) vs late (LFP) follicular phase (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: early (EFP) vs late (LFP) follicular phase… (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth or ongoing pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether intentional endometrial injury changes live birth or ongoing pregnancy (sensitivity analysis) compared with no intervention or a sham procedure (very low certainty).

1 finding from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Clinical pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
2 findings from 1 review

Intervention not reported

Live birth or ongoing pregnancy: prior cycle vs IUI cycle · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

It is very uncertain whether the intervention changes clinical pregnancy: prior cycle vs IUI cycle (sensitivity analysis) (very low certainty).

1 finding from 1 review