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What do systematic reviews say?

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Evidence found and GRADE certainty

1,562 questions · 1,645 findings · 107 reviews · Wounds

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No studies found 651 · 39.6%GRADE not reported 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Distilled water vs Normal saline

Infection · people with fractures

It is very uncertain whether distilled water changes infection compared with normal saline (very low certainty).

1 finding from 1 review

Tap water vs no wound cleansing

Wound healing · people with anal fissures

Tap water showed no clear difference in wound healing compared with no wound cleansing (low certainty).

1 finding from 1 review

Cooled boiled water vs Normal saline

Infection · people with fractures

It is very uncertain whether cooled boiled water changes infection compared with normal saline (very low certainty).

1 finding from 1 review

Distilled water vs cooled boiled water

Infection · people with fractures

It is very uncertain whether distilled water changes infection compared with cooled boiled water (very low certainty).

1 finding from 1 review

Tap water vs no wound cleansing

Reduction in wound size · people with anal fissures

The review found no eligible studies for this question.

1 finding from 1 review