What do systematic reviews say?

Prevention of eclampsia: IV maintenance vs standard IM maintenance regimen

It is very uncertain whether prevention of eclampsia: IV maintenance changes death of the baby before discharge: stillbirth compared with standard IM maintenance regimen (very low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 0.37 [0.02, 7.99]
  1 study · 17 participants
  Very low

Treatment of eclampsia: loading dose alone vs loading dose + maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: IV maintenance vs standard IM maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: IV maintenance vs standard IM maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

Prevention of eclampsia: short showed no clear difference in eclampsia compared with standard maintenance regimen (subgroups by type of short regimen) (low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 1.99 [0.18, 21.87]
  4 studies · 1713 participants
  Low

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

Prevention of eclampsia: short showed no clear difference in severe morbidity compared with standard maintenance regimen (subgroups by type of short regimen) (low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 0.96 [0.71, 1.29]
  2 studies · 1233 participants
  Low

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

Prevention of eclampsia: short showed no clear difference in side effect: respiratory depression compared with standard maintenance regimen (subgroups by type of short regimen) (low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 0.8 [0.25, 2.61]
  2 studies · 1424 participants
  Low

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: higher vs lower IV maintenance regimen

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 148 participants
  Very low

Prevention of eclampsia: higher vs lower IV maintenance regimen

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Very low

Treatment of eclampsia: loading dose alone vs loading dose + maintenance regimen

It is very uncertain whether treatment of eclampsia: loading dose alone changes maternal death compared with loading dose plus maintenance dose regimen (very low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 2.59 [0.11, 61.75]
  1 study · 80 participants
  Very low

Prevention of eclampsia: higher vs lower IV maintenance regimen

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 86 participants
  Very low

Prevention of eclampsia: higher vs lower IV maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: higher vs lower IV maintenance regimen

Prevention of eclampsia: higher showed no clear difference in side effects compared with lower IV maintenance regimen (low certainty).

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  RR 0.79 [0.61, 1.01]
  1 study · 62 participants
  Low

Prevention of eclampsia: higher vs lower IV maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: higher vs lower IV maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: higher vs lower IV maintenance regimen

The review found no eligible studies for this question.

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

• Alternative magnesium sulphate regimens for women with pre‐eclampsia and eclampsia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 200 participants
  Very low