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What do systematic reviews say?

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Evidence found and GRADE certainty

4,317 questions · 75,239 findings · 5,342 reviews

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No studies found 15,213 · 20.2%GRADE not reported 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

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Antibiotics vs other antibiotics

Adverse events considered non‐serious (penicillin versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus cefotaxime) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Adverse events considered non‐serious (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Non‐serious adverse events Maximum · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Adverse events considered non‐serious · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (penicillin versus a cephalosporin (cefotaxime or ceftriaxone)) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (penicillin versus a cephalosporin (cefotaxime… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (penicillin versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (penicillin versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (doxycycline versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (doxycycline versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy

Anastomotic leakage · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes incidence of anastomotic leakage compared with roux‐en‐Y reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy

Incidence of bile reflux · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes incidence of bile reflux compared with roux‐en‐Y reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy

Incidence of remnant gastritis · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes incidence of remnant gastritis compared with roux‐en‐Y reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy

Incidence of oesophagitis · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes incidence of oesophagitis compared with roux‐en‐Y reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy

Major postoperative complications · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes major postoperative complications compared with billroth II reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy

Anastomotic leakage · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether summary of findings table ‐ Uncut Roux‐en‐Y reconstruction changes incidence of anastomotic leakage compared with billroth II reconstruction after distal gastrectomy (very low certainty).

1 finding from 1 review